2005
DOI: 10.1001/archopht.123.9.1273
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Vision Loss Due to Macular Edema Induced by Rosiglitazone Treatment of Diabetes Mellitus

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Cited by 65 publications
(33 citation statements)
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“…La retención de líquidos es un factor que contribuye a empeorar el edema macular diabético y el tratamiento láser puede ser relativamente inefectivo hasta la eliminación del fluido 5 . El edema macular tiene un doble mecanismo: por aumento en el volumen plasmático y por aumento en la permeabilidad.…”
Section: Discussionunclassified
“…La retención de líquidos es un factor que contribuye a empeorar el edema macular diabético y el tratamiento láser puede ser relativamente inefectivo hasta la eliminación del fluido 5 . El edema macular tiene un doble mecanismo: por aumento en el volumen plasmático y por aumento en la permeabilidad.…”
Section: Discussionunclassified
“…As the pathologic mechanisms of major blinding diseases, such as age-related macular degeneration (AMD), diabetic retinopathy (DR), keratitis, and optic neuropathy, often involve neoangiogenesis and inflammation- and oxidative stress-mediated cell death, evidences are accumulating on the potential benefits of PPAR γ to improve or prevent these vision threatening eye diseases. However, there also several studies that reported the side effects of PPAR γ in some ocular diseases [3237]. In this paper we describe what is known about the role of PPAR γ in the ocular pathophysiological processes and PPAR γ agonists as novel adjuvants in the treatment of eye diseases.…”
Section: Introductionmentioning
confidence: 95%
“…Peripheral edema was shown to increase 3-fold with Avandia® treatment in comparison to control [41,42]. Macular edema incidence was also high with the consumption of Avandia® [43,44]. In addition, upper respiratory tract infection, headache, and cough symptoms were also noted.…”
Section: Biguanidesmentioning
confidence: 99%