This paper discusses the economic features of the current Covid-19 outbreak and its relation to labour markets and new skills in demand. At the same time, it focuses on how it started to expand worldwide, while reporting the ways of transmission and their effects on daily social and professional life. It is argued that focusing on skills and human capital could offer a strong foundation for building sustainable economies, as the recent months have been a suitable period to progress and advance digital skills, thus reducing digital illiteracy, while at the same time developing certain major sectors such as online education, ecommerce, telemedicine, entertainment, digital collaboration tools, virtual reality applications, etc. The author mainly focuses on the analysis of the recent global trends in many affected sectors, examines possible unemployment issues with an emphasis on the kind of new skills and soft skills in demand that are necessary for an easier transition to the new Covid-19 way of life.