Visual Acuity, Optical Components, and Macular Abnormalities in Patients with a History of Retinopathy of Prematurity

Wu, Wei‐Chi; Lin, Rui; Shih, Chia-Pang; Wang, Nan-Kai; Chen, Yen‐Po; Chao, An-Ning; Chen, Kuan‐Jen; Chen, Tun-Lu; Hwang, Yih‐Shiou; Lai, Chi-Chun; Huang, Chung‐Ying; Tsai, Shih‐Wei

doi:10.1016/j.ophtha.2012.02.040

Cited by 147 publications

(138 citation statements)

References 40 publications

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“…Many investigators have reported that ROP eyes have significantly steeper corneal curvatures, shallower anterior chamber depths, greater lens thicknesses, and increased macular thicknesses. 18,19 Our results further indicate that the high refractive errors in patients with additional laser treatment or LSV were not due to an increase in the AXL. It is most likely that the refractive errors of these patients are due to abnormalities in the anterior segment.…”

Section: Eyesupporting

confidence: 61%

“…5,7 Some studies have also found similar AXL measurements in patients with different severities of ROP. 18,19 It is now recognised that ROP and prematurityinduced myopia cannot be fully explained by increased AXL and that anterior segment arrest contributes to the increased myopia observed in these conditions. Many investigators have reported that ROP eyes have significantly steeper corneal curvatures, shallower anterior chamber depths, greater lens thicknesses, and increased macular thicknesses.…”

Section: Eyementioning

confidence: 99%

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Refractive errors after the use of bevacizumab for the treatment of retinopathy of prematurity: 2-year outcomes

Chen

et al. 2014

Eye

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Section: Eyesupporting

confidence: 61%

Section: Eyementioning

confidence: 99%

Refractive errors after the use of bevacizumab for the treatment of retinopathy of prematurity: 2-year outcomes

Chen

et al. 2014

Eye

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“…[1][2][3][4][12][13][14] Electroretinography also suggests that central retinal dysfunction is greater than peripheral dysfunction. 5 OCT has revealed changes not evident on ophthalmoscopy, but these can be compatible with good visual acuity.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have shown shallowing of the foveal depression, thickening of the central macula, and a continuity of inner retinal layers across the fovea in those born severely preterm, often despite normal macular appearance on ophthalmoscopy. [6][7][8][9][10][11][12][13][14] However, these macular changes evident on OCT are still compatible with good visual acuity. 6,7,[9][10][11] This has prompted authors to suggest that other factors might be contributory to the variation in vision seen in these patients.…”

Section: Introductionmentioning

confidence: 97%

Choroidal thickness in regressed retinopathy of prematurity

Anderson

Ramasamy

Lythgoe

et al. 2014

Eye

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Purpose To compare choroidal thickness in patients with regressed retinopathy of prematurity (ROP) with healthy controls using enhanced depth imaging optical coherence tomography (EDI OCT) Methods Twenty-four children and young adults (41 eyes) with regressed ROPZstage 3 had undergone EDI OCT with Spectralis FD-OCT as part of their clinical record. Their refraction, best-corrected visual acuity, and ophthalmoscopic findings were recorded. Corresponding data was collected prospectively from 33 healthy controls (58 eyes) who had been born at term. Choroidal thickness was measured independently by two observers subfoveally and at 1500 mm nasal and temporal to the fovea using EDI OCT. Results Mean subfoveal choroidal thickness, adjusted for refraction, was 271.1 mm (95% CI, 247.8-294.5) in the ex-ROP group, which was significantly thinner than 327.4 mm (95% CI, 293.8-360.9) in controls (P ¼ 0.008). Similarly, mean adjusted temporal choroidal thickness was 257.2 mm (95% CI, 240.2-274.2) in ex-ROP's vs 320.5 mm (95% CI, 288.6-352.3) in controls (P ¼ 0.001). There was no statistically significant difference in the nasal measurement. In the ex-ROP group, there was no significant correlation between subfoveal choroidal thickness and gestational age (r s ¼ 0.16, P ¼ 0.46) or birthweight (r s ¼ 0.03, P ¼ 0.90). In eyes without copathology in addition to regressed ROP (29 eyes, 19 patients), there was no significant correlation between subfoveal choroidal thickness and visual acuity. Conclusions Our findings of thinner subfoveal and temporal macular choroidal thickness in regressed ROP support the case for choroidal involvement in the pathogenesis of this condition.

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“…(Paired t-test, t=0.88, P-value=0.403). The CST values of both the MRNF and fellow eyes were also within the normal range [14]. The average macular thickness values for the 1mm central foveal subfield and for each quadrant of the 2 mm diameter circle are shown in Table 3.…”

Section: No Differences Detected In Macular Thicknessmentioning

confidence: 67%

Myelinated Retinal Nerve Fibers in Children: OCT Imaging, Refractive Error and Vision

O'Brien¹,

Sprunger²,

Lim³

et al. 2016

J Clin Exp Ophthalmol

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Visual Acuity, Optical Components, and Macular Abnormalities in Patients with a History of Retinopathy of Prematurity

Cited by 147 publications

References 40 publications

Refractive errors after the use of bevacizumab for the treatment of retinopathy of prematurity: 2-year outcomes

Refractive errors after the use of bevacizumab for the treatment of retinopathy of prematurity: 2-year outcomes

Choroidal thickness in regressed retinopathy of prematurity

Myelinated Retinal Nerve Fibers in Children: OCT Imaging, Refractive Error and Vision

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