Visual association encoding activates the medial temporal lobe: A functional magnetic resonance imaging study

Dementia in Down’s syndrome: an MRI comparison with Alzheimer’s disease in the general population

“…The medial temporal lobe plays an important role in the storage of new information [81,82] and atrophy of the medial temporal lobe may explain why memory dysfunction is an early symptom of AD [83,84]. Consistent with this, subjects with memory impairment who do not meet the criteria for dementia have an increased risk of subsequent AD [85-87].…”

Audio-visual crossmodal interactions in environmental perception: an fMRI investigation

“…Anatomical and physiological evidence demonstrated that the hippocampus receives projections from several senses (Mesulam 1998), through converging sensory input from the entorhinal, perirhinal and parahippocampal cortices. A number of studies (Eichenbaum 1992;Bunsey and Eichenbaum 1996;Henke et al 1997;Rombouts et al 1997) have underlined the importance of the hippocampus in associative learning, especially in tasks where participants are required to link multiple stimuli. According to Jackson and Schacter (2004), the hippocampal and medial temporal regions are specifically involved in the creation of durable links between individual items of information.…”

The fraction of an action is more than a movement: Neural signatures of event segmentation in fMRI

“…Sommer and co-workers (Sommer et al, 2005) found that a comparable segment of the parahippocampal gyrus was associated equally with the retrieval of objects based on location cues and the retrieval of locations based on object cues. Moreover, several neuroimaging studies have put forward a more general role of the parahippocampal gyrus or cortex in associative memories, as it is active during encoding and retrieval of associative information (Düzel et al, 2003;Eldridge et al, 2000;Henke et al, 1997;Krause et al, 1999;Rombouts et al, 1997). Hence this area engages during both scene processing and episodic retrieval because both rely on associations (Bar et al, 2008), i.e., spatial as well as non-spatial ones (Aminoff et al, 2007;however, cf.…”