Visual cognitive dysfunction in depression: an event-related potential study

Bange, François; Bathien, N

doi:10.1016/s0168-5597(98)00024-0

Cited by 68 publications

(26 citation statements)

References 35 publications

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“…Although the most common result associates a delay in P3b with clinical depression (Bange and Bathien, 1998;Kayser et al, 2000), our results are supported by those of a recent study investigating subclinical levels of depression associated with co-morbid anxiety by means of an emotional (visual) oddball design (Rossignol et al, 2008) which found no significant differences in P3b latencies between the control and the experimental group. To replicate this absence of effect, we intentionally selected two groups of people as similar as possible in age and gender, in order to increase the possibility that they would not show any significant differences on RTs and P3b latencies when performing a simple oddball task.…”

Section: Discussionsupporting

confidence: 88%

Is two better than one? A cross-modal oddball paradigm reveals greater sensitivity of the P300 to emotional face-voice associations

Campanella¹,

Bruyer

Froidbise

et al. 2010

Clinical Neurophysiology

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a b s t r a c tObjective: Studies exploring neurophysiological correlates of main psychiatric disorders have commonly used event-related potentials (ERP) during a visual or an auditory oddball task. The main results concern modulations of the P3b amplitude and/or latency. The present study aims to increase the clinical sensitivity of these P3b modulations by using a more ecological oddball design, using synchronized pairs of audio-visual emotional stimuli. Method: Two groups of healthy participants, one composed of controls and the other of students displaying anxious and depressive tendencies completed visual, auditory and audio-visual (cross-modal) oddball tasks, in which they had to detect deviant happy and sad stimuli among neutral ones as quickly as possible. Behavioral performance and P3b ERP data were analyzed. Results: Subjects displaying anxious and depressive tendencies exhibited lower P3b amplitude than the controls, but only in the cross-modal oddball task. Conclusions: Although the two groups of subjects differed in their levels of co-morbid anxiety and depression, unimodal visual and auditory oddball tasks did not allow us to detect this difference by P3b amplitude modulations, but the cross-modal task did. Significance: These results suggest that a cross-modal oddball design should be used in future studies to increase the sensitivity of the P300 amplitude differences between healthy participants and those with clinical symptoms.

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Section: Discussionsupporting

confidence: 88%

Is two better than one? A cross-modal oddball paradigm reveals greater sensitivity of the P300 to emotional face-voice associations

Campanella¹,

Bruyer

Froidbise

et al. 2010

Clinical Neurophysiology

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“…Numerous event-related brain potential (ERP) studies suggested that depressive patients exhibited deficits in attention and memory processes [17][18][19][20][21] . The ERP paradigm we used for exploring memory processing was a continuous word recognition test, in which correctly classified old items elicit more positive-going waveforms than new items after word presentation (e.g.…”

Section: Introductionmentioning

confidence: 99%

S100B Serum Levels and Word Memory Processing in Remitted Major Depression as Reflected by Brain Potentials

Zhang

Rothermundt²,

Peters³

et al. 2009

Neuropsychobiology

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Objective: Memory processes, as reflected by ‘old/new’ effects of event-related potentials (ERPs), have been shown to be impaired in depressed patients. This variability might be partly explained by biological factors. S100B is a glial calcium-binding protein with neuroplastic properties; S100B serum levels have been shown to be increased in depressive patients. The pathophysiologic role of S100B in depression, however, is not yet sufficiently understood. Methods: In the present study, ERPs recorded in a visual continuous word recognition paradigm were therefore investigated in patients with remitted major depression in relation to S100B serum levels. Results: Patients with moderately increased S100B serum levels (n = 6) showed a normal old/new effect in contrast to a reduced old/new effect in patients with normal S100B levels (n = 6) compared to aged-matched controls. Conclusions: These findings provide evidence of an association between S100B levels and memory processes in patients with recurrent depression and further suggest a neuroprotective role of moderately increased S100B serum levels in the course of affective disorders.

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“…In depression, the P3 latency of event-related potentials (ERP) elicited in an oddball paradigm has been shown in various papers to be increased compared to healthy volunteers (Bruder et al 1991;Bange and Bathien 1998;Vandoolaeghe et al 1998;Himani et al 1999). The P3 amplitude has been reported to be reduced for the most part (Blackwood et al 1987;Gangadhar et al 1993;Yanai et al 1997), although one study demonstrated unchanged amplitudes (Bange and Bathien 1998).…”

mentioning

confidence: 99%

The astroglial protein S100B and visually evoked event-related potentials before and after antidepressant treatment

et al. 2004

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Visual cognitive dysfunction in depression: an event-related potential study

Cited by 68 publications

References 35 publications

Is two better than one? A cross-modal oddball paradigm reveals greater sensitivity of the P300 to emotional face-voice associations

Is two better than one? A cross-modal oddball paradigm reveals greater sensitivity of the P300 to emotional face-voice associations

S100B Serum Levels and Word Memory Processing in Remitted Major Depression as Reflected by Brain Potentials

The astroglial protein S100B and visually evoked event-related potentials before and after antidepressant treatment

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