Visual inspection with acetic acid and cytology as screening methods for cervical lesions in Cameroon

Abstract

VIA has acceptable test qualities and may in low resource settings be implemented as a large scale screening method.

Comparison between Pap smear and visual inspection with acetic acid in screening of premalignant cervical intraepithelial lesion and subclinical early cancer cervix

“…Doh concluded that PAP smear was more specific but not sensitive as VIA test but both were compared to each other and VIA test can be used in low resource settings as in poor developing countries to screen wide mass population. 19 Another study was done by Goel in India for 400 women attending the gynaecological outpatient clinic in New Delhi and found that the sensivity of VIA test was 96.7% compared to 50% for PAP test and specificity was 36.4% compared to 97 for PAP test and the conclusion was that VIA test has a very high sensivity and very low cost that make it suitable for a primary screening test for cervical premalignant lesions in poor developing countries. 20 Our results showed that the sensitivity of PAP test was 83.3%, specificity was 90.7%, positive predictive value was 50.8%, negative predictive value was 97.9% and accuracy was 90% while the VIA test has a sensitivity of 66.7%, specificity was 91%, positive predictive value was 46.1%, negative predictive value was 95.9% and accuracy was 88.5%.…”

Accuracy of visual inspection with acetic acid in cervical ectopy evaluation

“…It was also in agreement with the findings of Cronje et al 2003 who reported in their study about comparison of four screening methods for cervical neoplasia in a developing country that the specificity of VIA was 48.5%. [19] However this result was in disagreement with the findings of Sankaranarayanan et al [8,20] who reported a much higher VIA specificity of 65% & 81.9%, respectively.…”

Acetic acid Visualisation of Cervix as an Alternative Screening Method for Cervical Cancer in Low Resource Settings

“…PPV of VIA was 44% and NPV was 91.3%. He concluded that though PAP has slightly better testing qualities but VIA has acceptable test qualities and can be implemented as a large scale screening method (11) . Shankaranarayanan and Mahe have published results comparing VIA to cytology and to HPV DNA testing and found that all three had similar detection rate of CIN 2 and 3 lesions and the range of sensitivity for VIA was 67-79% and specificity 49-86% (12) .…”