Visual outcomes of dense pediatric cataract surgery in eastern China

Ma, Fangqin; Ren, Meiyu; Wang, Lihua; Wang, Qi; Guo, Jingli

doi:10.1371/journal.pone.0180166

Cited by 12 publications

(6 citation statements)

References 30 publications

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“…We identified a statistically significant greater number of patients with nystagmus at last follow-up in the aphakic than in the IOL group. Furthermore, nystagmus was diagnosed more often in the bilateral than in the unilateral group at last follow-up, as also documented in other studies [ 18 , 43 , 44 ]. However, the small number of patients does not allow us to confirm a higher likelihood of nystagmus in children after bilateral than in unilateral cataract surgery.…”

Section: Discussionsupporting

confidence: 84%

Outcome of Pediatric Cataract Surgeries in a Tertiary Center in Switzerland

Ambroz

Töteberg‐Harms

Hanson

et al. 2018

Journal of Ophthalmology

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Purpose To determine and to analyze the outcome of pediatric cataract surgery. Methods A retrospective chart review of individuals aged up to 10 years who underwent cataract surgery between January 1, 2004, and December 31, 2014, at the UniversityHospital Zurich, Switzerland. Results 63 children (94 affected eyes) with bilateral (68/94) or unilateral (26/94) cataract were identified. Surgery was performed at a median age of 1.5 months (IQR: 1.3–2.6 months) for the aphakic group (45/94) and of 50.7 months (IQR: 38.0–78.4 months) for the IOL group (49/94). At the last follow-up visit (median 31.1 months, IQR: 18.4–50.2 months), visual acuity was better in bilateral than in unilateral cataract cases. Posterior capsular opacification (PCO) was diagnosed in 30.9% of eyes without a significant difference in the IOL and aphakic groups (p = 0.12). Aphakic glaucoma was diagnosed in 12/45 eyes at a median of 6.8 months (IQR 2.1–13.3 months) after surgery. Microcornea (5/12) and anterior segment anomalies (8/12) were associated with glaucoma development (p < 0.05). Conclusion Laterality and timing of surgery influence the outcome of pediatric cataract surgery. PCO was the most frequent postoperative complication. Aphakic glaucoma is often associated with ocular developmental abnormalities and a poor visual outcome.

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Section: Discussionsupporting

confidence: 84%

Outcome of Pediatric Cataract Surgeries in a Tertiary Center in Switzerland

Ambroz

Töteberg‐Harms

Hanson

et al. 2018

Journal of Ophthalmology

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“…Only 5.6% of children with more than 1 year follow-up were still blind. Our results compared in the Tables 3 and 4 are somewhere in between these two series and go in line with other case series from Shandong, China 13 and Gondar, Ethiopia 14 indicating that there is a good chance that a prospective study in Kinshasa (or a similar situation) could further improve the results in the near future.…”

Section: Discussionsupporting

confidence: 89%

Bilateral paediatric cataract surgery - outcomes of 298 children from Kinshasa, the Democratic Republic of the Congo

Ngoy

Stahnke²,

Dinkulu

et al. 2020

Afr H. Sci.

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Introduction: The leading cause of childhood blindness globally is paediatric cataract. Bilateral cataract surgery can help to improve visual performance and to diminish the burden of childhood blindness. Objective: To report in a retrospective observational cohort study the long-term outcomes of 298 children who had bilat- eral cataract surgery with IOL implantation from 2001-2016 in Kinshasa. Methods: A standardized surgical treatment of paediatric cataract was practiced on 298 children. Patient’s follow-up, com- plications, and visual outcomes were recorded and analysed. Results: The mean age was 5.7 ± 4.3 years and males were predominant (64.9%). Most of children were living mainly in urban poorest areas (96.3%). Strabismus, nystagmus and microcornea were encountered in 20.1%, 25.1% and 8.7% of children, respectively. Using WHO criteria most of patients were classified as blind preoperatively and 81.9% of them had improved visual outcomes after surgery. Main reasons for reduced vision during follow-up were secondary cataract (5.7%), IOL decentration (1.2%), retinal detachment (1.2%), and secondary glaucoma (1.5%). Conclusion: In spite of the post conflict challenges, elimination of cataract blindness in children remains a priority. Children present at a late age for surgery and long term follow-up is poor. There is need for program strengthening in these areas. Keywords: Paediatric cataract surgery; bilateral cataract; outcomes.

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“…There are several notable aspects of the vision of children treated for congenital cataracts (29), including a lack of accommodation [given the fixed-focus aphakic correction comprising either intraocular lenses (IOLs) or external glasses], changes in ocular growth (30), and the development of deprivation-induced amblyopia (31,32). The studies have spanned a spectrum of ages [with age at surgery ranging from less than 6 mo (33-35) to 8 y (36,37)].…”

Section: Significancementioning

confidence: 99%

Potential downside of high initial visual acuity

Vogelsang

Gilad-Gutnick

Ehrenberg

et al. 2018

Proc. Natl. Acad. Sci. U.S.A.

116

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Children who are treated for congenital cataracts later exhibit impairments in configural face analysis. This has been explained in terms of a critical period for the acquisition of normal face processing. Here, we consider a more parsimonious account according to which deficits in configural analysis result from the abnormally high initial retinal acuity that children treated for cataracts experience, relative to typical newborns. According to this proposal, the initial period of low retinal acuity characteristic of normal visual development induces extended spatial processing in the cortex that is important for configural face judgments. As a computational test of this hypothesis, we examined the effects of training with high-resolution or blurred images, and staged combinations, on the receptive fields and performance of a convolutional neural network. The results show that commencing training with blurred images creates receptive fields that integrate information across larger image areas and leads to improved performance and better generalization across a range of resolutions. These findings offer an explanation for the observed face recognition impairments after late treatment of congenital blindness, suggest an adaptive function for the acuity trajectory in normal development, and provide a scheme for improving the performance of computational face recognition systems.

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Visual outcomes of dense pediatric cataract surgery in eastern China

Cited by 12 publications

References 30 publications

Outcome of Pediatric Cataract Surgeries in a Tertiary Center in Switzerland

Outcome of Pediatric Cataract Surgeries in a Tertiary Center in Switzerland

Bilateral paediatric cataract surgery - outcomes of 298 children from Kinshasa, the Democratic Republic of the Congo

Potential downside of high initial visual acuity

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