Visual performance comparison of 2 extended depth-of-focus intraocular lenses

Schojai, Merita; Schultz, Tim; Jerke, Corinna; Böcker, Jörg; Dick, H. Burkhard

doi:10.1097/j.jcrs.0000000000000068

Cited by 36 publications

(44 citation statements)

References 13 publications

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“…Results with this lens and the levels of monovision tested appear better than were achieved with an aberration free lens based on spherical aberration that included a higher level of monovision in the non-dominant eye (mean −1.38 D). 11 The defocus curves with −0.50 D and −1.00 D in the non-dominant eye both also appear better than results for the IC-8 small aperture lens with 0.75 D of monovision 17 and the Symfony lens with various levels of monovision. 9 , 18 These results may be in part a function of the longer range of vision with the Vivity IOL measured here when both eyes were corrected for emmetropia.…”

Section: Discussionmentioning

confidence: 79%

The Effect of Spectacle-Induced Low Myopia in the Non-Dominant Eye on the Binocular Defocus Curve with a Non-Diffractive Extended Vision Intraocular Lens

Gundersen¹,

Potvin²

2021

OPTH

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Purpose: To quantify the changes in the binocular defocus curve associated with the Vivity™ non-diffractive extended vision intraocular lens when the dominant eye was targeted for emmetropia and the non-dominant eye was artificially targeted for slight myopia using spectacles. Patients and Methods: This was a non-interventional research study of the corrected binocular defocus curve associated with binocular emmetropia (Setting A) and with emmetropia in the dominant eye and two different levels of myopia simulated in the non-dominant eye (−0.50 D, Setting B and −1.00 D, Setting C). Subjects were patients implanted with the AcrySof ® IQ Vivity ® intraocular lens in both eyes 3 to 12 months previously. Using the defocus data, the percentage of subjects with a continuous 2.5 D range of vision (distance to 40 cm) was calculated for various levels of minimum visual acuity (VA). Results: Forty subjects were enrolled. The mean spherical equivalent refraction was −0.06 D ± 0.36 D, with 0.37 D ± 0.29 D of refractive cylinder. There was no statistically significant difference in the mean VA at −0.25 D or at −0.50 D vergences between the test Settings, but there was a statistically significant difference at all other vergences. Differences were particularly noticeable at −2.00 D, −2.50 D and −3.00 D, where higher myopia in the nondominant eye yielded better binocular VA. A 2.5 D range of functional vision (20/25) was achieved by 38% of subjects at Setting A, 68% of subjects at Setting B and 85% of subjects at Setting C. At setting C, all but one subject (39/40, 97.5%) had a 2.5 D range of vision with a VA of 20/32 or better. Conclusion: Significant gains in binocular near vision, with only a nominal effect on distance vision, can be achieved with the Vivity IOL by leaving the non-dominant eye of patients with 0.50 D or 1.00 D of myopia.

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Section: Discussionmentioning

confidence: 79%

The Effect of Spectacle-Induced Low Myopia in the Non-Dominant Eye on the Binocular Defocus Curve with a Non-Diffractive Extended Vision Intraocular Lens

Gundersen¹,

Potvin²

2021

OPTH

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“…Good performance with the Tecnis Symfony IOL has also been reported in other studies. [15][16][17][18][19][20][21][22][23] A potential benefit of EDOF IOLs compared to bifocal and trifocal IOLs is that visual disturbances may be reduced. This is because EDOF IOLs split light in a more continuous fashion, stretching a specific focal point rather producing several distinct focal points.…”

Section: Introductionmentioning

confidence: 99%

<p>Comparing Visual Acuity, Low Contrast Acuity and Contrast Sensitivity After Trifocal Toric and Extended Depth of Focus Toric Intraocular Lens Implantation</p>

Gundersen¹,

Potvin²

2020

OPTH

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The aim of this study was to compare visual acuity at various distances (far, intermediate and near), low contrast acuity and contrast sensitivity after trifocal toric and extended depth of focus (EDOF) toric intraocular lens (IOL) implantation. Patients and Methods: This was a non-interventional two-arm comparative study of visual outcomes after uncomplicated bilateral cataract or refractive lens exchange surgery with IOL implantation between 6 months and 5 years before a single diagnostic examination visit. There was no masking and no control group. Subjects had to have uncorrected distance visual acuity (UDVA) of 20/40 (0.3 logMAR) or better measured at the time of their study visit. Clinical evaluations included the manifest refraction, visual acuity (VA) at distance, intermediate (60 cm) and near (40 cm), low contrast (10%) VA and contrast sensitivity. Results: A total of 50 bilaterally implanted patients (25 trifocal, 25 EDOF) were examined; the two groups had similar characteristics, including corneal astigmatism. Postoperative refractive outcomes were also similar. There were no statistically significant differences in distance or intermediate VA between groups, but the trifocal group had significantly better near VA both uncorrected (p = 0.009) and distance-corrected (p = 0.014). There were no statistically significant differences in the low contrast acuity measures between IOLs at either distance or 40 cm, with or without glare. Contrast sensitivity in mesopic and photopic conditions was similar. Conclusion: The trifocal and EDOF toric IOLs performed similarly for all measures except near VA, where the trifocal toric provided significantly better acuity. For subjects interested in reducing spectacle independence at near, this may be an important consideration.

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“…The near visual performance with EDOF IOLs may be enhanced with a minimal residual myopic error in the nondominant eye or in both eyes. 10,14,22 This approach has been used in our series, with a mean postoperative spherical equivalent of −0.76 ± 0.53 D due to the inclusion of 4 micro-monovision cases. This explains the difference between monocular postoperative UNVA (0.11 ± 0.15 logMAR) and DCNVA (0.37 ± 0.36 logMAR), with values of this last visual parameter consistent with those reported for other refractive and diffractive EDOF IOLs.…”

Section: Discussionmentioning

confidence: 99%

“…1,2,4,[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] A common finding with all types of EDOF IOLs is an effective visual restoration at intermediate vision, but the level of near vision achieved varies significantly among IOL models. 1,2,4,[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] A novel recent EDOF approach has been developed for presbyopia correction based on the combination of primary and secondary spherical aberrations of opposite signs with a transition zone to a peripheral monofocal area (Synthesis PLUS, Cutting Edge, Montpellier, France). The theoretical aim of this new design is to deliver continuous high-contrast vision from distance to intermediate vision, while maintaining a functional level of near vision and preserving the ocular optical quality within an acceptable range to avoid the induction of light disturbances, such as halos, glare or starbursts.…”

Section: Introductionmentioning

confidence: 99%

Clinical Outcomes with a Novel Extended Depth of Focus Presbyopia-Correcting Intraocular Lens: Pilot Study

Iradier¹,

Cruz²,

Gentile³

et al. 2021

OPTH

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Purpose: To evaluate the clinical outcomes of cataract surgery with implantation of a novel model of extended depth of focus (EDOF) intraocular lens (IOL). Methods: Pilot case series enrolling a total of 27 eyes of 16 patients (49 to 84 years) undergoing uncomplicated phacoemulsification cataract surgery with implantation of the EDOF IOL Synthesis PLUS (Cutting Edge, Montpellier, France). Near (UNVA, uncorrected near visual acuity; DCNVA, distance-corrected near visual acuity) and distance visual acuity (uncorrected and corrected distance visual acuity, UDVA and CDVA), monocular defocus curve and refractive outcomes were evaluated during a 3-month follow-up. Results: Mean postoperative UDVA, UNVA and DCNVA were 0.11±0.17, 0.14±0.22 and 0.37 ±0.36 logMAR, respectively. A total of 84.6%, 91.7%, and 96.3% of eyes achieved postoperative UDVA, UNVA and CDVA of 0.20 logMAR or better. A total of 78.6% of eyes achieved postoperative DCNVA of 0.30 logMAR or better. Mean postoperative spherical equivalent was −0.76±0.53 D. The distance-corrected visual acuity was maintained on average over a value of 0.30 logMAR for the range of defocus levels between +1.00 and −1.50 D. Conclusion: The implantation of the Synthesis plus EDOF IOL after cataract surgery seems to provide functional levels of distance, intermediate and near visual acuity. The near visual performance with this new IOL might be significantly enhanced using a micro-monovision approach. The results of this pilot study should be confirmed in future clinical trials.

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Visual performance comparison of 2 extended depth-of-focus intraocular lenses

Cited by 36 publications

References 13 publications

The Effect of Spectacle-Induced Low Myopia in the Non-Dominant Eye on the Binocular Defocus Curve with a Non-Diffractive Extended Vision Intraocular Lens

The Effect of Spectacle-Induced Low Myopia in the Non-Dominant Eye on the Binocular Defocus Curve with a Non-Diffractive Extended Vision Intraocular Lens

<p>Comparing Visual Acuity, Low Contrast Acuity and Contrast Sensitivity After Trifocal Toric and Extended Depth of Focus Toric Intraocular Lens Implantation</p>

Clinical Outcomes with a Novel Extended Depth of Focus Presbyopia-Correcting Intraocular Lens: Pilot Study

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