Visual sensors of an inverse opal hydrogel for the colorimetric detection of glucose

Abstract

Possessing the combined advantages of a stable network structure, brilliant structural color, and high sensitivity, the three-dimensional inverse opal hydrogel film could be used as a colorimetric sensor for the precise detection of glucose.

Photonic crystal based biosensors: Emerging inverse opals for biomarker detection

“…The application of IOH as a colorimetric biosensor has been considered for the detection of biomolecules. In this regard, a unique and facile glucose detection method based on the IO polymer hydrogels was developed [ 108 ]. The vertical deposition method of SiO 2 microspheres was carried out for preparation of IOH structures, the opal template was formed and then the mixture of acrylamidophenylboronic acid as a monomer, ethylene glycol dimethyl acrylate as cross-linking agent and azobis as a radical initiator was filled over the SiO 2 PC template.…”

“…The vertical deposition method of SiO 2 microspheres was carried out for preparation of IOH structures, the opal template was formed and then the mixture of acrylamidophenylboronic acid as a monomer, ethylene glycol dimethyl acrylate as cross-linking agent and azobis as a radical initiator was filled over the SiO 2 PC template. Finally, the polymerization was performed under UV irradiation [ 108 ]. The IOH structure was detected sugars with 1,2-cis-diol function and it is useful for naked-eye diagnosis of diabetes.…”

Hydrogel-Based Colloidal Photonic Crystal Devices for Glucose Sensing

“…Thus, a wearable contact lens glucose sensor with colorimetric measurement was successfully proposed. Recent research works incorporated molecular imprinting technology to improve the specific recognition of glucose molecules, and thus improve the sensitivity and accuracy of the sensor [69][70][71][72].…”

Responsive principles and applications of smart materials in biosensing

“…Asher and co-workers first integrated PCs within hydrogels to regulate photonic band gaps and to achieve intelligent chemical sensing [ 48 ], then many biosensors with PC structures have been reported. For example, Zhao and coworkers developed a novel optical glucose sensor based on inverse opal hydrogels [ 49 ]. They used 3-APBA as a functional monomer and ethylene glycol dimethyl acrylate (EGDMA) as a cross-linking agent to prepare the inverse opal hydrogels ( Fig.…”