Visual Simultaneity Judgments Activate a Bilateral Frontoparietal Timing System

Hanayik, Taylor; Yourganov, Grigori; Newman‐Norlund, Roger; Gibson, Makayla; Rorden, Chris

doi:10.1162/jocn_a_01357

Cited by 5 publications

(11 citation statements)

References 40 publications

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“…As described thus far, the present fMRI study indicates that the right IPL is a neural correlate of tactile SJ. A similar right parietal area was also detected in audio-visual SJ 11 and visual SJ 37 . On the other hand, these studies also found SJ-specific activity in the right IFG and anterior insula, and the left cerebellum for audio-visual SJ 11 and in the bilateral IFG and the left TPJ for visual SJ 37 .…”

Section: Discussionsupporting

confidence: 58%

“…A similar right parietal area was also detected in audio-visual SJ 11 and visual SJ 37 . On the other hand, these studies also found SJ-specific activity in the right IFG and anterior insula, and the left cerebellum for audio-visual SJ 11 and in the bilateral IFG and the left TPJ for visual SJ 37 . The neural activity of audio-visual SJ was detected using a colour judgement with attending to sounds for a control task, and that of visual SJ was detected using visual-orientation and colour judgements for control tasks.…”

Section: Discussionsupporting

confidence: 58%

“…Thus, visual SJ activated the left IPL (included in TPJ) but not the right IPL. However, a recent fMRI study 37 detected SJ-specific activity not only in the left but also in the right TPJ by measuring more participants [ n = 14 in Lux et al . 12 , n = 35 in Hanayik et al .…”

Section: Discussionmentioning

confidence: 99%

“…12 , n = 35 in Hanayik et al . 37 . Moreover, the cluster size of the SJ-related activation area was larger for the right TPJ (cluster size: 961) than for the left TPJ (cluster size: 691) [see Table 1 and Fig.…”

Section: Discussionmentioning

confidence: 99%

“…2 in Hanayik et al . 37 ]. This current evidence suggests the involvement of the right IPL in visual SJ.…”

Section: Discussionmentioning

confidence: 99%

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Neural correlates of tactile simultaneity judgement: a functional magnetic resonance imaging study

Kimura

Kadota

Kuroda

et al. 2019

Sci Rep

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Simultaneity judgement (SJ) is a temporal discrimination task in which the targets span an ultimately short time range (zero or not). Psychophysical studies suggest that SJ is adequate to probe the perceptual components of human time processing in pure form. Thus far, time-relevant neural correlates for tactile SJ are unclear. We performed functional magnetic resonance imaging (fMRI) to investigate the neural correlates of tactile SJ using tactile number judgement as a time-irrelevant control task. As our main result, we demonstrated that the right inferior parietal lobule (IPL) is an SJ-specific region. The right IPL was detected by both parametric and non-parametric statistical analyses, and its activation intensity fulfilled a strict statistical criterion. In addition, we observed that some left-dominant regions (e.g., the striatum) were specifically activated by successive stimuli during SJ. Meanwhile, no region was specifically activated by simultaneous stimuli during SJ. Accordingly, we infer that the neural process for tactile SJ is as follows: the striatum estimates the time interval between tactile stimuli; based on this interval, the right IPL discriminates the successiveness or simultaneity of the stimuli. Moreover, taking detailed behavioural results into account, we further discuss possible concurrent or alternative mechanisms that can explain the fMRI results.

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Section: Discussionsupporting

confidence: 58%

Section: Discussionsupporting

confidence: 58%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…2 in Hanayik et al . 37 ]. This current evidence suggests the involvement of the right IPL in visual SJ.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Neural correlates of tactile simultaneity judgement: a functional magnetic resonance imaging study

Kimura

Kadota

Kuroda

et al. 2019

Sci Rep

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The neuroanatomy of visual extinction following right hemisphere brain damage: Insights from multivariate and Bayesian lesion analyses in acute stroke

Sperber,

Wiesen,

Karnath

et al. 2024

Human Brain Mapping

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Multi‐target attention, that is, the ability to attend and respond to multiple visual targets presented simultaneously on the horizontal meridian across both visual fields, is essential for everyday real‐world behaviour. Given the close link between the neuropsychological deficit of extinction and attentional limits in healthy subjects, investigating the anatomy that underlies extinction is uniquely capable of providing important insights concerning the anatomy critical for normal multi‐target attention. Previous studies into the brain areas critical for multi‐target attention and its failure in extinction patients have, however, produced heterogeneous results. In the current study, we used multivariate and Bayesian lesion analysis approaches to investigate the anatomical substrate of visual extinction in a large sample of 108 acute right hemisphere stroke patients. The use of acute stroke patient data and multivariate/Bayesian lesion analysis approaches allowed us to address limitations associated with previous studies and so obtain a more complete picture of the functional network associated with visual extinction. Our results demonstrate that the right temporo‐parietal junction (TPJ) is critically associated with visual extinction. The Bayesian lesion analysis additionally implicated the right intraparietal sulcus (IPS), in line with the results of studies in neurologically healthy participants that highlighted the IPS as the area critical for multi‐target attention. Our findings resolve the seemingly conflicting previous findings, and emphasise the urgent need for further research to clarify the precise cognitive role of the right TPJ in multi‐target attention and its failure in extinction patients.

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Paradoxical Sensitivity to Sub-threshold Asynchronies in Schizophrenia: A Behavioral and EEG Approach

Marques-Carneiro

Krieg

Duval

et al. 2021

Schizophrenia Bulletin Open

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The flow of consciousness is disrupted and disorganized in schizophrenia. We explore the hypothesis that this disruption is related to asynchronies not being predicted in advance and standing out instead of being integrated in the flow of events.We recorded EEG continuously during a simultaneity/asynchrony discrimination task, in which subjects decide whether two squares are shown simultaneously or with an asynchrony (asynchronies were between 24 and 96 ms). Behavioral data was obtained in 32 patients with schizophrenia and 27 matched controls, and EEG was recorded in a subset of 17 patients vs. 15 controls. Two results suggested a lack of asynchrony prediction in patients. Behavioral difficulties at detecting asynchronies increased in patients with schizophrenia relative to controls after a detection of simultaneity, and this effect was correlated with clinical disorganization. Desynchronization of alpha activity observed before the beginning of a trial was larger after asynchronous than simultaneous responses in controls, but not in patients. EEG signals additionally suggested abnormal sensitivity to short asynchronies in patients. The amplitude of early signals around 180 ms after the first square abnormally increased in patients for short asynchronies relative to perfect simultaneity, whereas EEG signals at parietal regions decreased in amplitude in patients relative to controls, in the 400-600 ms interval after the first square. These results reinforce the hypothesis of time prediction and sequencing impairments at the sub-second level, and may provide an explanation for the disruption of the patients’ consciousness flow.

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Visual Simultaneity Judgments Activate a Bilateral Frontoparietal Timing System

Cited by 5 publications

References 40 publications

Neural correlates of tactile simultaneity judgement: a functional magnetic resonance imaging study

Neural correlates of tactile simultaneity judgement: a functional magnetic resonance imaging study

The neuroanatomy of visual extinction following right hemisphere brain damage: Insights from multivariate and Bayesian lesion analyses in acute stroke

Paradoxical Sensitivity to Sub-threshold Asynchronies in Schizophrenia: A Behavioral and EEG Approach

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