Visualization of the Nuclei of the Basal Melanocytes of the Black Guinea-pig and of Human Skin under the Bright Field Microscope

The origin of Langerhans’ cell from the melanocyte

“…The cell, stained after dem elanisation (figs. 11-13,15) revealed a singular, large, basophilic, egg-shaped and twonotched central nucleus (Shukla [1965]); and sparse neutrophilic cytoplasm packed with granules of melanin (figs.21 23, 25 inn). The dendritic processes were disposed either horizontally or vertically to the body of the m elanocyte (Shukla et al [1954], fig.35).…”

The nature of dendritic cells of the epidermis of the white guinea pig

“…1972], juxtanuclcar and polar Golgi substance [Shukla andShanua. 1973] and a large vesic ular nucleus occupying nearly two thirds of the cytoplasm [Shukla, 1965] in the basal melanocyte of the white and black-and-white guinea pig and human beings, and the observation that the degeneration of the melanocyte was characterized by liquefaction of mitochondria, fractionation and localization of the Golgi substance around half the circumference of the nucleus in the intermediate stage and absence of mitochondria and perinuclear distribution of the frac tionated Golgi substance and isochemical degeneration 1 Thanks are due to Mr. R. C. Bhagat for his valuableassistance in staining the slides and to Mr. Ashok Kumar for photomicrography. of the nucleus with denaturalization of DNA [Slwkla.…”