Vitamin A Palmitate–β-cyclodextrin inclusion complexes: Characterization, protection and emulsification properties

Vilanova, Neus; Solans, Conxita

doi:10.1016/j.foodchem.2014.12.015

Cited by 69 publications

(32 citation statements)

References 30 publications

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“…This is mainly because of a number of key applications of CDs and extensive usage of macrocyclic oligosaccharides in chemistry (analytical chemistry, separation sciences; e.g., as resolution enhancers, active components of extraction systems) [16–18], micro-electronics and microfluidics devices (components of sensing systems) [19, 20], medicine, pharmacy, and cosmetology (drug and bioactive components carriers) [21–24], as well as food industry (aroma carriers, biocomponents extraction, active components of smart food packaging systems) [25–27]. Most recently, there is also an extensive research focusing on their efficient encapsulation properties, working as free molecules or after incorporation within new polysaccharide-based nanomaterials [28, 29].…”

Section: Introductionmentioning

confidence: 99%

Unexpected differences between planar and column liquid chromatographic retention of 1-acenaphthenol enantiomers controlled by supramolecular interactions involving β-cyclodextrin at subambient temperatures

et al. 2017

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We report the results of experimental work focusing on host-guest supramolecular complex creation between macrocyclic compound (β-cyclodextrin) and 1-acenaphthenol enantiomers (racemic mixture) in liquid phase composed of 35% acetonitrile in water (v/v) at different temperatures ranging from 0 to 90 °C. Experimental setup involved several analytical protocols based on classical non-forced flow planar chromatography (RP-18 TLC plates), micro-TLC (RP-18 W HPTLC plates), column chromatography (HPLC with C-18 and C-30 stationary phases), as well as UV-Vis spectrophotometry and optical microscopy. It has been found that under various planar chromatographic conditions (stationary plates type, chamber shape and volume, development mode, and saturation) non-typical retention properties (extremely high retention) of 1-acenaphthenol at subambient temperatures can be observed. To our knowledge, reported experimental results are in opposition to currently described retention models based on column chromatographic investigation of host-guest complexes (where in case of strong interaction of given analyte with macrocyclic mobile phases additive, which itself is non strongly retarded by stationary phase—close to the retention of dead volume marker, the retention of target compounds is shortened at low temperatures). To explain this TLC phenomenon that may have in our opinion a number of practical applications, especially for selective high throughput separation involving microchromatographic and/or microfluidic devices as well fractionation and extraction protocols (using, e.g., bar extraction systems), several experiments were conducted focusing on (i) acenaphthenol chromatography under different instrumental conditions, (ii) cyclodextrin retention measured as analyte or mobile phase additive, (iii) plate development time under different mobile phases and temperature settings, (iv) various column chromatographic conditions including C-30 and two C-18 stationary phases, (v) UV-Vis spectrophotometry, and (vi) microscopy inspection of precipitated CD-acenaphthenol crystals. Analysis of collected data has revealed that the most probable reasons for TLC retention behavior of 1-acenaphthenol under β-cyclodextrin additive conditions can be associated with (i) solubility changes of created host-guest complex, (ii) kinetics of solid complex precipitation, and (iii) differences in analysis time between planar and column chromatography. Because precipitation phenomenon may have a massive impact on analytes quantification involving macrocycles as the mobile phase additives, our previously reported data concerning a number of low-molecular compounds (mainly steroids and non steroidal endocrine disrupting chemicals) using HPLC methodology based on binary mobile phases without and with β-cyclodextrin and its hydroxypropyl derivative were re-examined and results discussed. Considering these data and the whole data set reported presently, the enhanced model of chromatographic retention driven by host-guest interaction was proposed.Electronic s...

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Section: Introductionmentioning

confidence: 99%

Unexpected differences between planar and column liquid chromatographic retention of 1-acenaphthenol enantiomers controlled by supramolecular interactions involving β-cyclodextrin at subambient temperatures

et al. 2017

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“…The spectrum of pure vitamin A (Figure 2b) showed the characteristic bands at 2922 and 2853 cm −1 of the free CH 3 group stretching, 1739 cm −1 correlated to the O-C=O stretching, and various peaks from 1460 to 1160 cm −1 related to the -CO groups stretching [9,66,67]. A peak at~1500 cm −1 could be attributed to the aromatic cyclohexene stretching [9,68].…”

Section: Structural Analysismentioning

confidence: 99%

Encapsulation of Vitamins A and E as Spray-Dried Additives for the Feed Industry

Mujica

Cháfer

Barra³

et al. 2020

Molecules

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Encapsulated fat-soluble powders containing vitamin A (VA) and E (VE) were prepared as a feasible additive for extruded feed products. The effect of the encapsulating agents (Capsul-CAP®, sodium caseinate-SC) in combination with Tween 80 (TW) as an emulsifier and maltodextrin (MD) as a wall material on the physicochemical properties of emulsions and powders was evaluated. First, nanoemulsions containing MD:CAP:TW:VA/VE and MD:SC:TW:VA/VE were prepared and characterized. Then, powders were obtained by means of spray-drying and analyzed in terms of the product yield, encapsulation efficiency, moisture content, porosity, surface morphology, chemical structure, and thermal properties and thermo-oxidative/thermal stability. Results showed that although nanoemulsions were obtained for all the compositions, homogeneous microcapsules were found after the drying process. High product yield and encapsulation efficiency were obtained, and the presence of the vitamins was corroborated. The characteristics of the powders were mainly influenced by the encapsulating agent used and also by the type of vitamin. In general, the microcapsules remained thermally stable up to 170 °C and, therefore, the proposed encapsulation systems for vitamins A and E were suitable for the preparation of additives for the feed manufacturing through the extrusion process.

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“…Vilanova and Solans [138] studied the inclusion complexes of Vitamin A Palmitate with β-cyclodextrins, without the use of organic solvents. The low stability and low water solubility of some vitamins limit its use as a food additive, so the authors' interest was to use cyclodextrin as an encapsulating agent to overcome these deficiencies, making possible the production of foods enriched with vitamins, in order to prevent diseases related to their deficiency.…”

Section: Cyclodextrins In Thermal Protectionmentioning

confidence: 99%

β-Cyclodextrins as Encapsulating Agents of Essential Oils

Capelezzo¹,

Mohr²,

Dalcanton³

et al. 2018

Cyclodextrin - A Versatile Ingredient

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Many scientific studies have made advances in the ability to encapsulate natural extracts by cyclodextrins. These studies have addressed the physical and chemical conditions of the encapsulation reactions, employed several types of essential oils and characterized the microcapsules as to their ability to release encapsulated active principles. The essential oils studies with cyclodextrin encapsulation processes have been highly varied. However, the most studied are the essential oils with antimicrobial and antioxidant capacities. The essential antimicrobial and antioxidant oils are easily degraded. In the presence of oxygen, they are oxidized, and at low temperatures, they are volatilized and decomposed. Thus, cyclodextrins are coatings capable of protecting these essential oils from environmental conditions and agents capable of promoting oil degradation, in addition to controlling their release. In this chapter of the book, we review scientific papers that examine the encapsulation of antimicrobial essential oils and antioxidant essential oils with β-cyclodextrins.

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Vitamin A Palmitate–β-cyclodextrin inclusion complexes: Characterization, protection and emulsification properties

Cited by 69 publications

References 30 publications

Unexpected differences between planar and column liquid chromatographic retention of 1-acenaphthenol enantiomers controlled by supramolecular interactions involving β-cyclodextrin at subambient temperatures

Unexpected differences between planar and column liquid chromatographic retention of 1-acenaphthenol enantiomers controlled by supramolecular interactions involving β-cyclodextrin at subambient temperatures

Encapsulation of Vitamins A and E as Spray-Dried Additives for the Feed Industry

β-Cyclodextrins as Encapsulating Agents of Essential Oils

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