The antagonism, or inverse correlation, between caries and periodontal disease has been the subject of much discussion among the members of the dental profession for some time. The literature itself is highly controversial in regard to the relationship between these factors. As far as we are aware, no actual proof of a relation has ever been offered. Many writers imply the premise that the two are antagonistic and advance various theories to explain the existence of this inverse correlation. Broderick (1, 2, 3, 4) interpreted the inverse relation as the result of biochemical phenomena, e.g., alkalosis or acidosis. He stated that a tendency toward sympathicotonia produces decreased alkalosis, or increased acidity, associated with a lymphocytosis, and brings about caries. On the other hand, a condition of vagotonia causes eosinophilia and an increased alkalinity which is associated with the production of pyorrhea. As opposed to Broderick, Citron (5) and Landgraf (6) reported diminished alkalinity of the blood in pyorrhea. Waiss (7) found neither of the above and stated that the alkali reserve in his cases of pyorrhea was well within normal limits.Bodecker (8)