“…Interestingly, VitD deficiency is reported to be associated, among others, with infection severity and incidence, inflammatory disease, mental health, metabolism, aging, immunological responses, carcinogenesis, and cancer prognosis [57,61,62]. VitD regulates a range of host defense mechanisms, including autophagy, apoptosis, cell differentiation, the release of cytokines and chemokines that promote inflammation, and, ultimately, the regulation of oxidative stress [40,61,63,64].…”