Vitamin C increases the fecal fat excretion by chitosan in guinea‐pigs, thereby reducing body weight gain

Jun, Sung Chul; Jung, Eun‐Young; Kang, Duk Ho; Kim, J. M.; Chang, Un Jae; Suh, Hyung Joo

doi:10.1002/ptr.2970

Cited by 12 publications

(7 citation statements)

References 51 publications

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“…A mild ascending trend in fecal fat excretion was noted among the three high fat groups on the order of HF (159.5 mg/day) < HF1X (165.0 mg/day) < HF2X (174.5 mg/day). As previously reported by Jun et al [ 19 ], there was a positive relationship between reduced dietary fat absorption and elevated fecal fat output.…”

Section: Resultssupporting

confidence: 80%

Inclusion of Fructooligosaccharide and Resistant Maltodextrin in High Fat Diets Promotes Simultaneous Improvements on Body Fat Reduction and Fecal Parameters

Kao

Chang

et al. 2018

Molecules

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This study investigated the effects of incorporating a mixture of fructooligosaccharide (FOS) and resistant maltodextrin (RMD) at a ratio of 1:2 on body fat accumulation and fecal bacterial parameters in rats. Our results indicated that high dietary fat consumption might effectively (p < 0.05) increase body fat, but consequently inducing a significantly (p < 0.05) higher growth of C. perfringens and retarded growth (p < 0.05) of the Bifidobacterium spp. in the large intestine. As compared with the high fat control, an incorporation of the FOS and RMD mixture at a high dose (0.97 and 1.94 g/kg body weight, respectively) could result in a significant (p < 0.05) reduction in feed efficiency (−16%), total visceral fat (−17.4%), non-visceral fat levels (−20.3%), and total body fat (−19.2%). Furthermore, feeding the FOS and RMD mixture at a high dose was capable to counter the above undesirable impacts by reducing the C. perfringens count (−14.8%) and increasing the total Bifidobacterium count (134.4%) and total fecal short chain fatty acids (195.4%). A supplementation of adequate amount of FOS and RMD might confer a concreted solution to the obesity and deteriorated fecal bacteria profiles due to high fat consumption.

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Section: Resultssupporting

confidence: 80%

Inclusion of Fructooligosaccharide and Resistant Maltodextrin in High Fat Diets Promotes Simultaneous Improvements on Body Fat Reduction and Fecal Parameters

Kao

Chang

et al. 2018

Molecules

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“…Among the four HF groups, a markedly higher (p < .05) fecal fat excretion (about 1.1-fold) was observed in the BC198S38 group (50.6 mg/g). As previously reported by Jun et al (2010), a higher fecal fat output was basically associated with a lesser extent of dietary fat absorption. These results demonstrated that the feeding of multi-strain mixture would lead to a higher fecal fat output in this study.…”

Section: Assessments On Fecal Moisture Weight Fat and Scfassupporting

confidence: 82%

Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota

Hsieh

You

Dai

et al. 2020

CyTA - Journal of Food

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Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota. This study investigated the effects of two single strains (Bacillus coagulans BC198 and Lactobacillus paracasei S38) at a level of 5 × 10 9 CFU and a mixture of these two strains (1 x 10 8 CFU) on body fat accumulation and gut microbiota in rats. In contrast to high-fat control, L. paracasei S38 intakes resulted in significant (p < .05) reductions in total visceral fat (−15%) and liver lipids (−19%). The supplementation of the multi-strain mixture at a relatively lower dose was more efficient (p < .05) in reducing feed efficiency (−17%), total visceral fat (−30%), and liver lipids (−32%). A higher concentration of total short-chain fatty acids and a higher proportion of Bacteroidetes were also observed in the fecal samples of the multi-strain group. Consumption of multiple strains of B. coagulans BC198 and L. paracasei S38 appeared to show greater efficacy than single strains even at a relatively low dose. El Bacillus coagulans BC198 y el Lactobacillus paracasei S38 combinados reducen la acumulación de grasa corporal y modulan la microbiota intestinal RESUMEN El presente estudio se propuso investigar los efectos de dos cepas individuales (Bacillus coagulans BC198 y Lactobacillus paracasei S38) a un nivel de 5 × 10 9 UFC y de una mezcla de estas dos cepas (1 x 10 8 UFC) en la acumulación de grasa corporal y la microbiota intestinal de las ratas. En contraste con el control de grasas, la ingesta de L. paracasei S38 provocó reducciones significativas (p < .05) de la grasa visceral total (−15%) y los lípidos hepáticos (−19%). La suplementación con la mezcla de múltiples cepas a una dosis relativamente más baja fue más efectiva (p < .05) para reducir la eficiencia de la alimentación (−17%), la grasa visceral total (−30%) y los lípidos hepáticos (−32%). Asimismo, se observó mayor concentración de ácidos grasos totales de cadena corta (SCFA) y mayor proporción de Bacteroidetes en las muestras fecales del grupo que consumió cepas múltiples. En conclusión, el consumo de cepas múltiples de B. coagulans BC198 y L. paracasei S38 parece tener mayor eficacia que las cepas individuales, incluso a una dosis relativamente baja, para reducir la acumulación de grasa corporal y modular la microbiota intestinal.

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“…Accumulating literature also link vitamin D studies with bones while comparing BMI and general weight gains [ 14 – 16 ]. On the other hand, vitamin C however, has completely different functions in an in vitro experiments and in humans [ 20 – 22 ]; some previous studies show that, the metabolism of glucose in the insulin resistant people was improved, and the blood pressure was lowered in patients who took vitamin C supplementation [ 23 ]. Furthermore, vitamin C and vitamin E supplementation are shown to prevent molecular regulators that trigger the sensitivity of insulin as well antioxidant defense mechanisms through physical activities [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

Comparative effects of vitamin D and vitamin C supplementations with and without endurance physical activity on metabolic syndrome patients: a randomized controlled trial

Farag

Hosseinzadeh‐Attar

Muhammad

et al. 2018

Diabetol Metab Syndr

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ObjectiveVitamin D and C levels have inverse relation with the metabolic syndrome components and they are used as antioxidant supplements during enduring metabolic activities. In the present study, we hypothesized that the intake of vitamin D and/or C with endurance physical activity might reduce the risk of metabolic syndrome.MethodsA randomized control study recruited 180 participants of both genders, aged between 30 and 50 years. The participants were assigned into six groups receiving different doses of vitamin D or vitamin C with or without physical activities. Data were collected over a period of 3 months, and the results were analyzed using SPSS version 20.ResultsVariations in the effect of the supplements on various body variables including: Fasting plasma glucose, total cholesterol, low-density lipoprotein cholesterol and blood pressure, showed that vitamin D has more influence compared to vitamin C. However, vitamin D and C supplements do not have any effect on weight when consumers are undergoing endurance physical exercise. But vitamin C consumer group has more effect in waist circumference, triglyceride, and high-density lipoprotein, as compared to vitamin D consumer group.ConclusionWe conclude that, consumption of vitamin D or vitamin C supplements may improves the life of metabolic syndrome patients. However, the combination of physical activities and vitamin supplements maximize the effect, and this combination should be recommended.Trial registration WHO-ICTRP IRCT20161110030823N2. Registered 01 February 2018. http://apps.who.int/trialsearch/Trial2.aspx?TrialID=IRCT20161110030823N2

show abstract

Vitamin C increases the fecal fat excretion by chitosan in guinea‐pigs, thereby reducing body weight gain

Cited by 12 publications

References 51 publications

Inclusion of Fructooligosaccharide and Resistant Maltodextrin in High Fat Diets Promotes Simultaneous Improvements on Body Fat Reduction and Fecal Parameters

Inclusion of Fructooligosaccharide and Resistant Maltodextrin in High Fat Diets Promotes Simultaneous Improvements on Body Fat Reduction and Fecal Parameters

Bacillus coagulans BC198 and Lactobacillus paracasei S38 in combination reduce body fat accumulation and modulate gut microbiota

Comparative effects of vitamin D and vitamin C supplementations with and without endurance physical activity on metabolic syndrome patients: a randomized controlled trial

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