Vitamin D and the mechanisms, circumstances and consequences of falls in older adults: A case-control study

Abstract

This case-control study reported that vitamin D deficiency was associated with falls in older inpatients. There was a greater prevalence of orthostatic hypotension and of the reccurrence of falls among fallers with vitamin D deficiency, suggesting that vitamin D may influence the conditions predisposing to falls rather than the fall by itself.

Circulating 25-hydroxyvitamin D concentration can predict bowel resection risk among individuals with inflammatory bowel disease in a longitudinal cohort with 13 years of follow-up

“…In the secondary analysis, we conducted analysis (1) recategorizing serum 25(OH)D concentration into four groups (≤25, 25 to≤50, 50 to≤75, and >75 nmol/l) with clinical relevance 25 , 26 ; (2) investigating associations between serum 25(OH)D and bowel resection risk by admission source; (3) exploring whether there is a difference in associations stratified by baseline bowel resection history; (4) investigating associations among IBD with the different Montreal phenotypes based on the ICD-10 codes 13 (Supplementary Table S1, Supplemental Digital Content 2, http://links.lww.com/JS9/C268 ); (5) assessing the associations stratified by median disease duration (≤15, >15 years) of participants when recruited.…”

Systematic causality mapping of factors leading to accidental falls of older adults

“…There are both intrinsic and extrinsic risk factors [ 9 ]. The intrinsic factors include but not limited to age, gender [ 10 , 11 ], chronic diseases, acute diseases (e.g., acute myocardial infarction) [ 12 ], and deficiency of vitamins (such as vitamin D deficiency) [ 13 ]. Studies showed that age [ [14] , [15] , [16] ] is a key risk factor because older adults tend to have issues like vertigo, poor posture stability [ 4 , 17 , 18 ], poor vision [ 4 , 15 , 17 , 19 ], frailty [ 20 , 21 ], and other ageing-associated diseases [ [22] , [23] , [24] , [25] , [26] ] that lead to falls.…”

Vitamin D: Does the Emperor Have No Clothes?

“…Over the last decade Vitamin D has become the magic elixir that is considered to help or prevent large numbers of health problems of older persons. Besides its effects on bone, vitamin D has been considered to be integral in the cause of immune dysfunction, falls, muscle weakness, cancer, cardiovascular disease, cognitive dysfunction, lung disease, stroke, paraplegia, benign paroxysmal positional vertigo; multiple sclerosis and depression (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14). Frailty is a major cause of poor outcomes in older individuals (15)(16)(17)(18)(19)(20)(21)(22) and has been associated with low levels of 25 (OH) Vitamin D (23)(24)(25)(26).…”