Vitamin D Deficiency in Pregnancy after Bariatric Surgery

Abstract

The objective of this study was to describe the main factors related to the installation and/or aggravation of vitamin D deficiency (VDD) and its clinical consequences in pregnant women after bariatric surgery. An electronic search on VDD in pregnancy and after bariatric surgery was conducted in publications from 1998 until 2012 that presented studies performed in humans. We provided an overview of VDD after bariatric surgery, in pregnancy, and in pregnancy in women who underwent bariatric surgery. In view of the high percentage of VDD postoperatively and the role of this vitamin in pregnancy, we recommend the investigation of vitamin D nutritional status in prenatal care.

Maternal Micronutrient Deficiencies and Related Adverse Neonatal Outcomes after Bariatric Surgery: A Systematic Review

“…The primary outcomes are depleted maternal concentrations or deficiencies of phylloquinone, folate, iron, calcium, zinc, magnesium, iodine, copper, and vitamins A, D, and B-12. The choice for these micronutrients was based on a nonsystematic descriptive overview study by Kaska et al (7), with the exception of vitamin D, which was added because of the relevant prevalence of deficiencies postoperatively and its important role in pregnancy (8). Secondary outcomes were fetal and neonatal complications related to low maternal micronutrient concentrations or deficiencies after bariatric surgery.…”

Vitamin D Deficiency in Brazil: Questions about Potential Causes and Clinical Characteristics*

“…This hypovitaminosis usually occurs in obese individuals in a 50% higher proportion compared to eutrophic subjects. 30 This finding may be related to the presence of vitamin D receptors in the adipose tissue, which would extract the vitamin from the blood circulation, reducing its concentration. In addition, obesity tends to reduce sunlight exposure due to mobility limitations.…”

Is Restrictive Bariatric Surgery Good Option in Improving Pregnancy Outcome in Obese Women?

“…The RYGB and BPD can cause chronic deficiencies in nutrients such as vitamins, folic acid, and albumin, high prevalence of vitamin A deficiency and D following bariatric surgery procedures. So, given the critical role of these micronutrients in proper fetal development, their watchful monitoring with biochemical tests is recommended for most pregnant women undergoing malabsorptive procedures [8].…”