Vitamin D status in healthy Moroccan men and women aged 50 years and older: a cross-sectional study

Maataoui, Aissam El; Biaz, Asmae; Machtani, Samira El; Bouhsain, Sanae; Dami, Abdellah; Maghraoui, A. El; Ouzzif, Z.

doi:10.1007/s11657-016-0279-y

Cited by 18 publications

(10 citation statements)

References 23 publications

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“…The high prevalence in the study conducted in Spain was not explained by geographic location or laboratory technique, and the most sensitive technique, HPLC, was used in that study. Morocco, the only African country represented in this review, accounted for three of the studies evaluated 30,32,36 , among which the prevalence ranged from 77.4%, in a study using electrochemiluminescence and collecting samples between November 2008 and October 2009 32 , to 92.0%, in a study using chemiluminescent immunoassay and collecting samples between June and August of an unspecified year 30 . These data did little to explain the difference found, given that the prevalence was higher in the study conducted only during the months of maximum solar radiation in that country 30 .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of hypovitaminosis D in postmenopausal women: a systematic review

Valladares

Simões

Bernardo

et al. 2019

Rev. Assoc. Med. Bras.

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SUMMARY BACKGROUND: Hypovitaminosis D is considered a global public health issue. Knowledge of its true dimensions will allow us to design interventions and plan preventive measures that can have a significant impact on human health. OBJECTIVES: The aim of this study was to evaluate the prevalence of hypovitaminosis D, defined as a serum 25-hydroxyvitamin D concentration < 30 ng/ml, in postmenopausal women around the world, as well as to identify the potential associated factors. METHODS: A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analyses recommendations. Specific search terms were consulted in Medline, Excerpta Medica, and Latin-American and Caribbean Health Sciences Literature databases, with no restriction for the year or language of publication. RESULTS: Of 451 studies initially identified, 32 were selected for analysis. Collectively, those 32 studies evaluated 21,236 postmenopausal women, of whom 16,440 (77.4%) had serum 25-hydroxyvitamin D concentrations < 30 ng/ml. The reported prevalence of hypovitaminosis D ranged from 29% (in the United States) to 99.4% (in China). In six of the studies, the prevalence was above 90%. CONCLUSIONS: If the criterion is the 30 ng/ml cut-off point, the majority of postmenopausal women in the world could be classified as having hypovitaminosis D. Among the studies evaluated, the lowest prevalence reported was nearly 30%. Neither latitude, region of the world, nor laboratory methodology were found to be associated with the prevalence of hypovitaminosis D.

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Section: Discussionmentioning

confidence: 99%

Prevalence of hypovitaminosis D in postmenopausal women: a systematic review

Valladares

Simões

Bernardo

et al. 2019

Rev. Assoc. Med. Bras.

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“…The study by Quaggiotto et al corroborated with the present study, showing from a laboratory databank analysis that high levels of 25(OH)D were detected in young individuals, while aged individuals presented the lowest values of 25(OH)D [ 20 ]. Other studies also suggest that vitamin D is prevalent among older people and could be a risk factor for the development of osteoporosis and osteomalacia [ 27 – 29 ]. Although many studies show a correlation between vitamin D deficiency and age, it is important to note that even healthy teenagers and children can bear vitamin D levels considered insufficient [ 24 , 25 ].…”

Section: Discussionmentioning

confidence: 99%

Vitamin D Status and Its Association with Parathyroid Hormone Concentration in Brazilians

Martins

Palhares

Teixeira

et al. 2017

Journal of Nutrition and Metabolism

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Vitamins are organic compounds that play a vital role in the control of metabolic processes. The D complex is considered a nutrient with a hormonal action and has an important participation in the constant maintenance of serum and extracellular calcium levels. The present study aims to analyze the results of 105.588 vitamin D (25(OH)D) measurements obtained from a database from a clinical analysis laboratory in Brazil, between the years of 2011 and 2013. The values of 25(OH)D were correlated with age, gender, and values of PTH. The results show a high prevalence of values of 25(OH)D considered inadequate, characterizing 76% of the studied population. It was observed that 26,5% of the individuals had deficiency and 49,5% had insufficiency of vitamin D. It was also shown that there was a negative correlation between 25(OH)D and PTH levels. In conclusion, this study is in accordance with others that show a high prevalence of vitamin D deficiency in different populations and alerts us for the importance of these measurements and analysis in clinical practice and as a base for diagnosis and treatment of hypovitaminosis.

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“…Vitamin D deficiency was reported by other studies concerning Moroccan population. [25][26][27] It is perhaps due to low quality of exposure and covering dress habits is recognized predisposing factor for hypovitaminosis D.…”

Section: Resultsmentioning

confidence: 99%

Serum vitamin D and vitamin D receptor gene polymorphism in Moroccan patients with systemic lupus erythematosus

et al. 2017

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Background: Vitamin D plays an important role in the immunomodulation and could be involved in the development of autoimmune diseases such as systemic lupus erythematous (SLE). The study of the polymorphism of the Vitamin D Receptor (VDR) gene may be of interest in explaining the pathophysiology of SLE.Methods: In this study, we aimed to examine the characteristics of VDR gene BsmI polymorphism for the first time in Moroccan patients with SLE and their relationship with clinical manifestations of the disease. We also measured the serum level of 25-hyroxyvitamin D3 to assess its relation to such polymorphism.Results: The study included 66 SLE patients and 91 healthy controls. Our results showed that there were no differences observed in VDR genotypes and allelic distribution within the two groups. Both groups were in Hardy-Weinberg equilibrium, with no significant P values for the observed and expected genotype frequencies. 25-hyroxyvitamin D3 serum levels were the same in the two groups.Conclusions: Based on the results of the present study. We cannot verify any association between VDR gene BsmI polymorphism and SLE. This polymorphism could not be regarded as a genetic marker of the SLE. A larger study examining BsmI and other VDR gene polymorphisms is needed.

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Vitamin D status in healthy Moroccan men and women aged 50 years and older: a cross-sectional study

Abstract: Despite a sunny environment, we found in this study a high prevalence of hypovitaminosis D (insufficiency + deficiency) in Moroccan men over 50 years old and postmenopausal women.

Cited by 18 publications

References 23 publications

Prevalence of hypovitaminosis D in postmenopausal women: a systematic review

Prevalence of hypovitaminosis D in postmenopausal women: a systematic review

Vitamin D Status and Its Association with Parathyroid Hormone Concentration in Brazilians

Serum vitamin D and vitamin D receptor gene polymorphism in Moroccan patients with systemic lupus erythematosus

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