Vitamin E increases prostate cancer risk in middle-aged men relative to placebo: no significant association observed with selenium, either alone or in combination with vitamin E

Abstract

Vitamin E increases prostate cancer risk in middle-aged men relative to placebo: no significant association observed with selenium, either alone or in combination with vitamin E Gwen Wyatt Implications for practice and researchClinicians should inform patients that vitamin E sig-■ nifi cantly increased the risk of prostate cancer among healthy men, and should be avoided. Extended follow-up of common doses of vitamins and ■ supplements may reveal new and critically signifi cant fi ndings.