Vitamin E: Nature’s Gift to Fight Cancer

Mutalip, Siti Syairah Mohd

doi:10.1007/978-981-10-8548-2_16

Cited by 3 publications

(3 citation statements)

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“…The latter compound contributes to the radiation ameliorating effect following accidental overexposure. Furthermore, Mutalip [ 54 ] reflected that better antioxidant properties were observed in tocotrienols compared to tocopherols. However, the literature reflected that tocotrienols showed a higher radioprotective effect in comparison with tocopherols, remembering that low bioavailability is a limiting factor in a clinical viewpoint when applied as radioprotectants [ 55 ].…”

Section: Resultsmentioning

confidence: 99%

Vitamins and Radioprotective Effect: A Review

et al. 2023

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The radioprotective effect ex vivo, in vitro and in vivo of vitamins was reviewed using PubMed and Embase and conducted according to the PRISMA statement. A total of 38 articles were included in this review, which includes the radioprotective effect of vitamins from ex vivo, in vitro and in vivo studies. Vitamins A, C, D and E were used alone, in combination or with other nutritional and non-nutritional compounds. The use of vitamins in natural form or supplementation can be useful to reduce the radiation effect in the body, organs and/or cells. Only four (A, C, D and E) out of thirteen vitamins have been detected with radioprotective properties being mainly vitamin E followed by vitamin C, A and D.

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Section: Resultsmentioning

confidence: 99%

Vitamins and Radioprotective Effect: A Review

et al. 2023

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“…The anticancer effects of vitamin E have been extensively shown with most researches proving vitamin E suppression of the proliferation and growth of cancer cells through various signaling pathways and mechanisms [6]. The reported studies were conducted on various cancer types as shown in Figure 1.…”

Section: Anticancer Effect Of Vitamin E On Cancersmentioning

confidence: 99%

“…This powerful fat-soluble vitamin is well known for its role as antioxidant [4,5] and anticancer, and extensive research was conducted to search for its potential use in cancer treatments. However, the reviewed literature showed that most of the efforts were spent on other types of cancers [6], but the gynecological ones. The studies involving gynecological cancers were shown to be limitedly available [7], with ovarian cancer being one of them.…”

Section: Introductionmentioning

confidence: 99%

A Review of the Effects of Vitamin E in Ovarian Cancer

Awang¹,

Mutalip²,

Mohamed³

et al. 2022

Int J Pharm Res Allied Sci

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Vitamin E is made up of two substances, tocopherols (TOCs) and tocotrienols (TCTs). These substances are present in four different subtypes namely alpha, beta, delta and gamma and these subtypes differs in their chemical structures. Vitamin E has been made known to exert anticancer effects for decades-long ago. This vitamin, which is also a well-known lipid-soluble antioxidant, has been extensively studied and its effects on cancer cells progressions are widely reported. These include its effects on the progressions of the breast, cervix, colon, liver, lung, pancreas, prostate, skin, and stomach cancers. Despite the widely available reports on vitamin E as an anticancer, the particular reports on the effects of this vitamin for reproduction in ovarian cancer are remarkably limited. Hence, this review is written to provide a summary of the reported effects from the studies published between the year 2010-2020 and the possible future research on vitamin E in ovarian cancer. This review will contribute to a more organized finding on the effects of vitamin E and ovarian cancer.

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