Volatile Components of<i>Pelargonium roseum</i>R. Br

Dabiri, Minoo; Sefidkon, Fatemeh; Yousefi, Maryam; Bashiribod, Sahareh

doi:10.1080/0972060x.2011.10643909

Cited by 7 publications

(6 citation statements)

References 7 publications

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“…Sesquiterpene hydrocarbons (19.8%) gave a minor contribution to the P. roseum EO, with δ‐selinene (5.5%), ( E )‐caryophyllene (2.6%), δ‐cadinene (2.5%), and β‐bourbonene (2.1%) as the most representative compounds. The chemical composition herein detected was consistent with that reported by Carmen and Hancu () and slightly different from that found by Dabiri, Sefidkon, Yousefi, and Bashiribod ().…”

Section: Resultssupporting

confidence: 86%

Anxiolytic and antidepressant activities of Pelargonium roseum essential oil on Swiss albino mice: Possible involvement of serotonergic transmission

Tabari

Moghaddam

Maggi

et al. 2018

Phytotherapy Research

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The anxiolytic and antidepressant activities of the Reunion Geranium (Pelargonium roseum Willd) essential oil (EO) were evaluated in male Swiss albino mice by intraperitoneal administration of 10, 20, and 50 mg/kg bw using elevated plus maze (EPM), open-field test (OFT), and forced swimming test (FST). Moreover, we evaluated whether the 5-HT and GABA -benzodiazepine receptor systems are involved in the anxiolytic effects through the coadministration of WAY-100635 (a selective 5-HT receptor antagonist) and flumazenil (an antagonist of benzodiazepine). GC-MS revealed the monoterpene alcohols citronellol (35.9%) and geraniol (18.5%) as the main components of the P. roseum EO. EO was effective in increasing the total number of entries and time spent in the open arms of EPM whereas number of rearing in OFT was significantly decreased in comparison with the control. In the FST, immobility time decreased in EO treated mice. Pretreatment with WAY-100635, but not Flumazenil, was able to reverse the effects of the EO in the EPM and FST, indicating that the EO activity occurs via the serotonergic but not GABAergic transmission. Overall, results of this work showed significant anxiolytic and antidepressant activity of P. roseum EO and confirmed the traditional uses of Pelargonium species as calming agents.

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Section: Resultssupporting

confidence: 86%

Anxiolytic and antidepressant activities of Pelargonium roseum essential oil on Swiss albino mice: Possible involvement of serotonergic transmission

Tabari

Moghaddam

Maggi

et al. 2018

Phytotherapy Research

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“…[ 10 11 ] In addition, they have local anti-inflammatory and local analgesic, antiseptic, and anti-oxidant effects. [ 12 13 17 ] The double-ring terpenoids present in the plant accelerate wound healing by increasing local blood flow; on the other hand, the herb is highly aromatic which gives pleasant smell and taste to the product. [ 10 12 ]…”

Section: Discussionmentioning

confidence: 99%

“…Geranium or Pelargonium roseum R. Br ( Geraniaceae ) has analgesic and anti-inflammatory effects due to compounds such as geraniol, citral, and citronellal. [ 17 ] In a study, the anti-infection of polyohenol extract and inhibition of virus proliferation and growth have been surveyed in the medium. [ 17 18 ]…”

Section: Introductionmentioning

confidence: 99%

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Design, formulation, and evaluation of a herbal gel contains melissa, sumac, licorice, rosemary, and geranium for treatment of recurrent labial herpes infections

2018

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Background:The herpes simplex virus is a human pathogen which can cause skin or mucous membrane infections. Melissa, sumac, licorice, rosemary, and geranium have antimicrobial, antiviral, anti-inflammatory, and local analgesic effect. Shortening recovery period of recurrent herpes labialis and control of viral protein formation are the other effects of these herbs. The aim of this study is design, formulation, and evaluation of the gel containing extracts of these five herbs.Materials and Methods:In this experimental study after photochemical and macroscopic evaluation of these medicinal herbs, the semisolid concentrated extracts were incorporated in gel bases. Mucoadhesive gels were prepared using carbopol 940, sodium carboxymethylcellulose (Na CMC) and hydroxypropyl methylcellulose K4M as bioadhesive polymers. Physicochemical tests, viscosity, mucoadhesive strength measurement, and in vitro drug release study were carried out on formulations F10 (carbopol 940, 0.5% and Na CMC, 3%) and F11 (carbopol 940, 1% and Na CMC, 3%).Results:Polyphenol content of extracts mixture was measured 210.8 ± 13.68 mg GAE/g. pH of formulations was 6.0 ± 0.2. 14 gel formulations were prepared. Physical appearance, homogeneity, and consistency of F10 and F11 were good. Mucoadhesion and viscosity of F11 was more than F10. Study of release profiles in F10 and F11 formulations showed drug release from F11 was slower.Conclusion:The best formulation for treatment and shortening recovery period of recurrent labial herpes infections should exhibit high value of mucoadhesion, show controlled release of drug. F11 with the highest viscosity and mucoadhesion and the lowest release rate was considered as the best formulation.

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“…According to the concentration causing 50% mortality (LC 50 ), all the tested oils were toxic to the Angoumois grain moth during 24 hours. Probit analysis, and ducial Limit (FL) showed that toxicity of the three oils including S. hortensis (LC 50 13.562 (11.978-15.323) μgL -1 (air)), P. roseum (LC 50 14.193 (13.044-15.575) μgL -1 (air)) and S. aromaticum (LC 50 14.189 (12.570-15.879) μgL -1 (air)) did not have any signi cant difference, while T. vulgaris (LC 50 20.125 (19.002-21.372) μgL -1 (air)) was less toxic against the adult moths (Table 2).…”

Section: Fumigant Toxicitymentioning

confidence: 97%

Toxicity effects of several medicinal plants essential oils on Angoumois grain moth (Sitotroga cerealella) female adults

Ghoorchian,

Rahmani,

Weisany

2023

J Plant Dis Prot

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The use of plant essential oils as eco-friendly and bio-rational insecticides has emerged as a promising alternative to hazardous fumigant pesticides for controlling stored product insect pests. This study investigated the vapor toxicity of essential oils obtained from the Lamiaceae, Geraniaceae, and Myrtaceae plant families against Sitotroga cerealella (Olivier) female adults, commonly known as the Angoumois grain moth. Gas chromatography-mass spectrometry analysis revealed Thymol (56.36%), Citronellol (39.7%), Eugenol (80.0%), and Carvacrol (42.28%) as the primary components in Thymus vulgaris, Pelargonium roseum, Syzygium aromaticum, and Satureja hortensis, respectively. Probit analysis and ducial Limit (FL) calculations determined the 24-hour toxicity (LC 50 ) of the essential oils diluted in acetone (10%), resulting in LC 50

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Volatile Components ofPelargonium roseumR. Br

Cited by 7 publications

References 7 publications

Anxiolytic and antidepressant activities of Pelargonium roseum essential oil on Swiss albino mice: Possible involvement of serotonergic transmission

Anxiolytic and antidepressant activities of Pelargonium roseum essential oil on Swiss albino mice: Possible involvement of serotonergic transmission

Design, formulation, and evaluation of a herbal gel contains melissa, sumac, licorice, rosemary, and geranium for treatment of recurrent labial herpes infections

Toxicity effects of several medicinal plants essential oils on Angoumois grain moth (Sitotroga cerealella) female adults

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