Volatile Constituents Composition of<i>Blepharocalyx salicifolius</i>Leaf Oil

Moreira, Jane J.S.; Pereira, Cristina Silva; Ethur, Eduardo Miranda; Machado, Emília Carolina; Morel, Ademir F.; König, Wielfried A.

doi:10.1080/10412905.1999.9701067

Cited by 5 publications

(4 citation statements)

References 7 publications

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“…The chemical composition of the essential oil in leaves extracted from this species has been reported and mainly includes 1,8-cineol, α-pinene, limonene, β-pinene, α-terpineol, ( E )-caryophyllene and linalool [ 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. However, few studies relating to the biological activities of the essential oil from this plant are available.…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Bioactivity of Essential Oil from Blepharocalyx salicifolius

Furtado

Borges

Teixeira

et al. 2018

IJMS

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Natural products represent a source of biologically active molecules that have an important role in drug discovery. The aromatic plant Blepharocalyx salicifolius has a diverse chemical constitution but the biological activities of its essential oils have not been thoroughly investigated. The aims of this paper were to evaluate in vitro cytotoxic, antifungal and antibacterial activities of an essential oil from leaves of B. salicifolius and to identify its main chemical constituents. The essential oil was extracted by steam distillation, chemical composition was determined by gas chromatography/mass spectrometry, and biological activities were performed by a microdilution broth method. The yield of essential oil was 0.86% (w/w), and the main constituents identified were bicyclogermacrene (17.50%), globulol (14.13%), viridiflorol (8.83%), γ-eudesmol (7.89%) and α-eudesmol (6.88%). The essential oil was cytotoxic against the MDA-MB-231 (46.60 μg·mL−1) breast cancer cell line, being more selective for this cell type compared to the normal breast cell line MCF-10A (314.44 μg·mL−1). Flow cytometry and cytotoxicity results showed that this oil does not act by inducing cell death, but rather by impairment of cellular metabolism specifically of the cancer cells. Furthermore, it presented antifungal activity against Paracoccidioides brasiliensis (156.25 μg·mL−1) but was inactive against other fungi and bacteria. Essential oil from B. salicifolius showed promising biological activities and is therefore a source of molecules to be exploited in medicine or by the pharmaceutical industry.

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Section: Introductionmentioning

confidence: 99%

Chemical Composition and Bioactivity of Essential Oil from Blepharocalyx salicifolius

Furtado

Borges

Teixeira

et al. 2018

IJMS

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“…In Uruguay, either an infusion or an alcoholic extract prepared with the leaves and fruits of this plant are used as tonic to alleviate the symptoms of indigestion and cough (Alonso and Desmarchelier, 2005). In southern Brazil, this plant is also used as external astringent in baths for the treatment of diarrhoea, leucorrhoea, urethritis and rectal prolapse (Mors et al 2000), as antirheumatic and hypoglycemic agent (Alice et al 1991), as diuretic and to treat stomach diseases (Moreira et al 1999).…”

Section: Introductionmentioning

confidence: 99%

“…The composition of the Blepharocalyx salicifolius essential oil (EO-Bs) varies among the regions where this species grows (Dellacasa et al 1997;Tucker et al 1993;Moreira et al 1999;Limberger et al 2001;Garneau et al 2013), but its main active component has recently been identified as 1,8-cineole (Garneau et al 2013). The active ingredient 1,8-cineole is also characteristic of the essential oil obtained from the leaves and fruits of Eucalyptus globulus; which is known to confer antiseptic and bronchodilating properties (Salari et al 2006;Mulyaningsih et al 2010).…”

Section: Introductionmentioning

confidence: 99%

Antitussive, antispasmodic, bronchodilating and cardiac inotropic effects of the essential oil from Blepharocalyx salicifolius leaves

Hernández

Ragone

Bonazzola

et al. 2018

Journal of Ethnopharmacology

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The results indicate that the preparations from Blepharocalyx salicifolius leaves were effective as central antitussive, bronchodilating and antispasmodic agents, suggestive of a mechanism associated with the inhibition of Ca influx into smooth muscle. The EO-Bs displayed only a poor ability to reduce cardiac inotropism, and was devoid of any cardioprotective properties. Thus, the present study validates the traditional use of this South American plant for asthma, cough and bronchospasm, shedding new light into its potency and putative mechanism of action.

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“…It is also used as hypotensive, astringent, antibacterial, and antispasmodic [8]. Recent reports investigating chemical composition of Blepharocalyx salicifolius EOs by GC-MS analysis have already found several constituents, such as 1,8-cineole, linalool, -caryophyllene [9], -pinene, limonene [10,11], myrcene, -pinene [11], spathulenol, and pinene [10]. Myracrodruon is a genus in the family Anacardiaceae, which presents tropical and subtropical distribution, comprising about 70 genera and 700 species [12].…”

Section: Introductionmentioning

confidence: 99%

Essential Oil Constituents and Yields from Leaves ofBlepharocalyx salicifolius(Kunt) O. Berg andMyracrodruon urundeuva(Allemão) Collected during Daytime

Costa

Menezzi

Benedito

et al. 2014

International Journal of Forestry Research

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The purpose of this study was to evaluate the essential oil composition and yield from leaves of two Brazilian species (Myracrodruon urundeuvaandBlepharocalyx salicifolius) harvested during daytime. Essential oils were obtained by steam distillation and had their yield determined.Blepharocalyx salicifoliuspresented yields of 0.049% (9 a.m.), 0.045% (1 p.m.), and 0.069% (5 p.m.). ForMyracrodruon urundeuva, we found 0.13% (9 a.m.), 0.11% (1 p.m.), and 0.08% (5 p.m.). Finally, compound identification and quantification were carried out by GC-MS and GC-FID techniques, respectively. Thirteen major compounds were identified forBlepharocalyx salicifolius, representing 91.6% of the EOs, of whichp-cymene (25.9%) was detected as amajor component. Nine major compounds were identified forMyracrodruon urundeuva, representing 90.3% of the EOs, whereasβ-myrcene showed the greatest concentration (66.4%).

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Volatile Constituents Composition ofBlepharocalyx salicifoliusLeaf Oil

Cited by 5 publications

References 7 publications

Chemical Composition and Bioactivity of Essential Oil from Blepharocalyx salicifolius

Chemical Composition and Bioactivity of Essential Oil from Blepharocalyx salicifolius

Antitussive, antispasmodic, bronchodilating and cardiac inotropic effects of the essential oil from Blepharocalyx salicifolius leaves

Essential Oil Constituents and Yields from Leaves ofBlepharocalyx salicifolius(Kunt) O. Berg andMyracrodruon urundeuva(Allemão) Collected during Daytime

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