This study explores students' misconceptions with the particulate concept of matter in gaseous state. Then, based on promoting students' learning and understanding from a constructivist perspective, the effectiveness of instructional activities by presenting a demonstration with computer simulation was investigated. Students were expected to benefit from computer monitored instruction in a number of ways: by becoming more interested in physical phenomena and therefore more motivated; by acquiring a concrete example of a abstract concept that will aid them in reasoning; and by being able to evaluate their predictions of a future physical event using their current conceptual framework and the new concept being presented in the teaching activity. A systematic study of students' ideas on particulate concepts was carried out first with the participation of 296 subjects in Grade 5-8 (age 11-12 through 14-15) inTaiwan. An open-ended questionnaire and picture drawing question was administered to the subjects. The responses were categorized according to the level of sophistication of the answer and the drawing of the picture. The instruments used both in the pretest and posttest were designed in a format of a two-tier test. Teaching is conducted by a computer demonstration that was specifically designed from implications regarding students' cognitive conflict. The research findings indicated that students had some misconceptions about the gaseous particles concerning the size, weight, motion and kinetic distribution in space. After teaching, there was a comparison of students' learning outcomes between the pretest and posttest. A significant difference statistically revealed that teaching activity in this research by the computer-simulated demonstration could obviously benefit students' conceptual change in learning of particulate theory.