VP05.01: Association of ductus venosus pulsatility index (DV PI) >1.3 with aneuploidies, cardiac and non‐cardiac defects at the 11⁺⁰–13⁺⁶ and 18⁺⁰–23⁺⁶ weeks' scan

Abstract

assessed. High risk results is based on cutoff 1/250, low risk results is based on cutoff 1/1500. Results: The results showed that the mean age of IVF and spontaneous pregnancy group was not significantly different. Comparison of BMI between two groups showed that BMI in the IVF pregnancy group was higher than spontaneous pregnancy group. Cases with twin fetuses, dichorionic twin pregnancy, and fetal anomaly were more found among IVF group. Although mean free β-hCG and PAPP.A were higher among cases with IVF, but these differences were not significant. IVF population had a significant higher proportion of NT more than 95th centile 61/373 (16%) in comparision with spontaneous pregnancy 102/1879 (5%). According to the first trimester test, in the IVF group 81.3% women had a high risk and 6.6% had a low risk, in spontaneous group 81.3% pregnancy had a high and 7.0% low risk. There was not significant different between two groups. Conclusions: This study showed that free β-hCG and PAPP.A, and High Risk results were not significantly different between IVF pregnancies and spontaneous pregnancies. But in terms of increased NT, there were significant difference in IVF and spontaneous pregnancies. Increased NT in IVF group were associated with higher risk for fetal anomalies (rather than aneuploidy). So this study reemphasises on usefulness of first trimester scan in IVF pregnancies with special atention to fetal anatomy. VP05: EARLY MARKERS OF ABNORMAL DEVELOPMENT VP05.01 Association of ductus venosus pulsatility index (DV PI) >1.3 with aneuploidies, cardiac and non-cardiac defects at the 11 +0-13 +6 and 18 +0-23 +6 weeks' scan