Listeria monocytogenes invades epithelial cells by binding to the host cell receptor E-cadherin, a component of the adherens junction. E-cadherin serves primarily as an adhesive to mediate bacterial invasion; the canonical E-cadherin/catenin/F-actin complex is not required for this process.
We have established the nasal bone length in South Indian fetuses at 16-26 weeks of gestation and there is progressive increase in the fifth percentile of nasal bone length with advancing gestational age. Hence, gestational age should be considered while defining hypoplasia of the nasal bone.
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