Investigating the impact of near-field ground motions on the fragility curves of multi-span simply supported concrete girder bridges is the main goal of this paper. Fragility curves are valuable tools for evaluating seismic risks and vulnerabilities of bridges. Numerous studies have investigated the impact of ground motions on the fragility curves of bridges. Ground motions are commonly categorized into two sets, based on the distance of the recorded station from the seismic source: far-field and near-field. Studies examining the influence of near-field records on bridge fragility curves vary depending on the specific bridge type and type of fragility curve being analyzed. Due to the widespread use of multi-span simply supported concrete girder bridges in the Central and Southeastern United States, this study makes use of this bridge type. This research investigates the component fragility curves for column curvatures, bearing deformations, and abutment displacements by employing 3-D analytical models and conducting nonlinear time history analysis. These curves illustrate the impact of near-field ground motions on different components. The component fragility curves for two sets of records, 91 near-field ground motions and 78 far-field ground motions, were obtained and compared. These findings demonstrate that near-field ground motions have a greater damaging effect on columns and abutments than far-field earthquakes. When it comes to bearing deformations, the far-field earthquake impact is more severe at lower intensities, whereas the impact of the near-field ground motion is stronger at higher intensities.