The importance of groundwater is growing based on an increase in need and decrease in the availability of fresh surface water sources and adequate rainfall. Remote Sensing and Geographic Information System (GIS) has become one of the leading tools in the field of hydrogeological science, which helps in assessing, monitoring and conserving groundwater resources. This paper describes the results of a groundwater potentiality and quality assessment conducted in Koduvan Ár sub-watershed of Meenachil river basin, Kottayam district of Kerala state, in the Republic of India. Shallow groundwater is the main source of drinking water in urban and rural areas, but reliable spatial data on its potentiality and quality are currently insufficient for developing the water-supply systems with standard designs. The methodology used in the present study includes an integrated approach of remote sensing and GIS for the construction of groundwater potentiality map and the assessment of water quality of identified wells. Different spatial data layers such as, geomorphology, lithology, slope and land use/ land cover are generated and the interrelationship between these layers were analyzed to identify and assess the groundwater potentiality of the area. The final result depicts the favourable prospective zones in the study area with its quality parameters and can be helpful to formulate recommendations to reduce the water scarcity and quality risks for public health.