W1370 Absorptive Capacity of Fructans in Healthy Humans: A Dose Response Study

Donahoe, R.; Attaluri, Ashok; Schneider, Margot; Valestin, Jessica; Rao, Satish S.

doi:10.1016/s0016-5085(10)63261-1

Cited by 2 publications

(3 citation statements)

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“…The most common structural forms of fructan are inulin, levanare and geraminan. The human body has limited ability to break down these oligo- or polysaccharides in the small bowel and only absorbs 5 – 15% of fructan [22, 23]. The mechanism for malabsorption and intolerance is related to the lack of enzymes to fully hydrolyze glycosidic linkages in the complex polysaccharide, and therefore results in the malabsorbed fructans to be delivered to the colon, which are then fermented [24].…”

Section: Fructan Intolerancementioning

confidence: 99%

“…There are only a few studies on absorptive capacity of fructan in humans [27, 28]. A preliminary report suggests that a dose of 7.5 g may be the optimal dose for breath testing of up to 3 hours in fructan intolerance [23]. In this dose-ranging response study, 14 healthy subjects, in a random order, were subjected to 7.5, 10 or 12.5 g of 10% fructan (chicory inulin) solution at weekly interval.…”

Section: Fructan Intolerancementioning

confidence: 99%

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Dietary Fructose Intolerance, Fructan Intolerance and FODMAPs

Fedewa

Rao

2013

Curr Gastroenterol Rep

133

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Dietary intolerances to fructose, fructans and FODMAPs (Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyols) are common, yet poorly recognized and managed. Over the last decade, they have come to the forefront because of new knowledge on the mechanisms and treatment of these conditions. Patients with these problems often present with unexplained bloating, belching, distension, gas, abdominal pain or diarrhea. Here, we have examined the most up-to-date research on these food-related intolerances, discussed controversies, and have provided some guidelines for the dietary management of these conditions. Breath testing for carbohydrate intolerance appears to be standardized and essential for the diagnosis and management of these conditions, especially in the Western population. While current research shows that the FODMAP diet may be effective in treating irritable bowel syndrome, additional research is needed to identify more foods items that are high in FODMAPs, and to assess the long-term efficacy and safety of dietary interventions.

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Section: Fructan Intolerancementioning

confidence: 99%

Section: Fructan Intolerancementioning

confidence: 99%

Dietary Fructose Intolerance, Fructan Intolerance and FODMAPs

Fedewa

Rao

2013

Curr Gastroenterol Rep

133

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“…Breath test showed that all subjects developed mild flatulence, burping, feeling of fullness and bloating. 14 According to a study conducted in China, headache was most prevalent issue due to Monosodium glutamate. 15 In 2017, a study was conducted by Acker 16 in Boston to determine prevalence of food intolerance and food allergy in males and females.…”

Section: Introductionmentioning

confidence: 99%

Impact of food intolerance on quality of life among university students

Kamran¹,

Imtiaz²,

Amin³

et al. 2020

JPCPY

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Background: Food intolerance is prevalent in the modern world. Based on the methods of data collection and definitions it influences up to 15-20 percent of the population. Objective: To find out impact of food intolerance on quality of life among universitystudents. Methodology: A cross-sectional study was conducted among 250 students, selected from The University of Lahore through non-probability convenience sampling. Data were collected about their socio-demographics using self-reported questionnaire and quality of life using QOL-BREF questionnaire. Analysis of association between different variables was done using chi square test. Results: 81 (32%) subjects were male while 169 (68%) subjects were female. 225 (90%) students were undergraduate and 25 (10%) were postgraduate. 209 (83.6%) students were food intolerant while 41 (16.4%) students were having no food intolerance issue. The mean score of subjects in physical, psychological, social and environmental domain of QOL-BREF was 59.80±14.984, 57.92±16.791, 32.47±14.047 and 59.94±15.465 respectively.No significant association was found between intolerance to food and quality of life of subjects. Conclusion: Food intolerance had no impact on quality of life of the subjects. There was no impact of food intolerance on quality of life among university students. Social domain had the minimum score and environmental domain had maximum score among all domains of QOL-BREF

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W1370 Absorptive Capacity of Fructans in Healthy Humans: A Dose Response Study

Cited by 2 publications

References 0 publications

Dietary Fructose Intolerance, Fructan Intolerance and FODMAPs

Dietary Fructose Intolerance, Fructan Intolerance and FODMAPs

Impact of food intolerance on quality of life among university students

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