Waist circumference as a measure for indicating need for weight management

Lean, Michael E. J.; Han, Thang S.; Morrison, Caroline

doi:10.1136/bmj.311.6998.158

Cited by 1,507 publications

(1,216 citation statements)

References 20 publications

Supporting

Mentioning

1,043

Contrasting

Unclassified

135

Order By: Relevance

“…As a measure of both overall obesity and central obesity, we determined the optimal cut-off points for WC. These cut-off points were in agreement with internationally used cut-off points as determined by Lean et al (1995): 102 cm for men and 88 cm for women.…”

Section: Anthropometrysupporting

confidence: 86%

See 1 more Smart Citation

Waist circumference as a measurement of obesity in the Netherlands Antilles; associations with hypertension and diabetes mellitus

et al. 2004

View full text Add to dashboard Cite

Objectives: To evaluate waist circumference (WC) as a screening tool for obesity in a Caribbean population. To identify risk groups with a high prevalence of (central) obesity in a Caribbean population, and to evaluate associations between (central) obesity and self-reported hypertension and diabetes mellitus. Design: Cross-sectional. Setting: Population-based study. Subjects: A random sample of adults (18 y or older) was selected from the Population Registries of three islands of the Netherlands Antilles. Response was over 80%. Complete data were available for 2025 subjects. Intervention: A questionnaire and measurements of weight, height, waist and hip. Main outcome measurement: Central obesity indicator (WC Z102 cm men, Z88 cm women). Results: WC was positively associated with age (65-74 y vs 18-24 y) in men (OR ¼ 7.7, 95% CI 3.4-17.4) and women (OR ¼ 6.4, 95% CI 3.2-12.7). Women with a low education had a higher prevalence of central obesity than women with a high education (OR ¼ 0.5, 95% CI 0.3-0.7). However, men with a high income had a higher prevalence of a central obesity than men with a low income (OR ¼ 1.7, 95% CI ¼ 1.1-2.6). WC was the strongest independent obesity indicator associated with self-reported hypertension (OR ¼ 1.7, 95% CI 1.4-2.0) and diabetes mellitus (OR ¼ 1.6, 95% CI 1.3-1.9). Conclusions: The identified risk groups were women aged 55-74 y, women with a low educational level and men with a high income. WC appears to be the major obesity indicator associated with hypertension and diabetes mellitus.

show abstract

Section: Anthropometrysupporting

confidence: 86%

“…For international comparison, we used the cut-off values proposed by Lean et al (1995), that is, a WHR equal to or greater than 0.95 for men and 0.80 for women.…”

Section: Anthropometrymentioning

confidence: 99%

Waist circumference as a measurement of obesity in the Netherlands Antilles; associations with hypertension and diabetes mellitus

et al. 2004

View full text Add to dashboard Cite

show abstract

“…Certain regions of the torso change in proportion to the change in body mass, where others show little change 39. Waist circumference is a good predictor of the body's adiposity 40, 41. For example, Tovée et al9 report that the waist width of 134 adult women is correlated at r > 0.90 with their BMI, whereas higher and lower regions of their torso show weaker correlations.…”

Section: Discussionmentioning

confidence: 99%

Fixation patterns, not clinical diagnosis, predict body size over‐estimation in eating disordered women and healthy controls

Cornelissen

Hancock

et al. 2016

Intl J Eating Disorders

View full text Add to dashboard Cite

ObjectiveA core feature of anorexia nervosa (AN) is an over‐estimation of body size. Women with AN have a different pattern of eye‐movements when judging bodies, but it is unclear whether this is specific to their diagnosis or whether it is found in anyone over‐estimating body size.MethodTo address this question, we compared the eye movement patterns from three participant groups while they carried out a body size estimation task: (i) 20 women with recovering/recovered anorexia (rAN) who had concerns about body shape and weight and who over‐estimated body size, (ii) 20 healthy controls who had normative levels of concern about body shape and who estimated body size accurately (iii) 20 healthy controls who had normative levels of concern about body shape but who did over‐estimate body size.ResultsComparisons between the three groups showed that: (i) accurate body size estimators tended to look more in the waist region, and this was independent of clinical diagnosis; (ii) there is a pattern of looking at images of bodies, particularly viewing the upper parts of the torso and face, which is specific to participants with rAN but which is independent of accuracy in body size estimation.DiscussionSince the over‐estimating controls did not share the same body image concerns that women with rAN report, their over‐estimation cannot be explained by attitudinal concerns about body shape and weight. These results suggest that a distributed fixation pattern is associated with over‐estimation of body size and should be addressed in treatment programs. © 2016 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:507–518).

show abstract

“…A more sensitive measure is waist circumference, which gives information about the central fat distribution and is used to define abdominal obesity. 7 Although environmental factors have an important function, there is significant evidence for a heritable component in obesity. 8,9 In general, the total variance in BMI explained by genetic factors varies between 20 and 90%, with a most probable value around 40%.…”

Section: Introductionmentioning

confidence: 99%

Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study

et al. 2009

View full text Add to dashboard Cite

Background: As nuclear receptors and transcription factors have an important regulatory function in adipocyte differentiation and fat storage, genetic variation in these key regulators and downstream pathways may be involved in the onset of obesity. Objective: To explore associations between single nucleotide polymorphisms (SNPs) in candidate genes from regulatory pathways that control fatty acid and glucose metabolism, and repeated measurements of body mass index (BMI) and waist circumference in a large Dutch study population. Methods: Data of 327 SNPs across 239 genes were analyzed for 3575 participants of the Doetinchem cohort, who were examined three times during 11 years, using the Illumina Golden Gate assay. Adjusted random coefficient models were used to analyze the relationship between SNPS and obesity phenotypes. False discovery rate q-values were calculated to account for multiple testing. Significance of the associations was defined as a q-value p0.20. Results: Two SNPs (in NR1H4 and SMARCA2 in women only) were significantly associated with both BMI and waist circumference. In addition, two SNPs (in SIRT1 and SCAP in women only) were associated with BMI alone. A functional SNP, in IL6, was strongly associated with waist. Conclusion: In this explorative study among participants of a large population-based cohort, five SNPs, mainly located in transcription mediator genes, were strongly associated with obesity phenotypes. The results from whole genome and candidate gene studies support the potential role of NR1H4, SIRT1, SMARCA2 and IL6 in obesity. Although replication of our findings and further research on the functionality of these SNPs and underlying mechanism is necessary, our data indirectly suggest a role of GATA transcription factors in weight control.

show abstract

Waist circumference as a measure for indicating need for weight management

Cited by 1,507 publications

References 20 publications

Waist circumference as a measurement of obesity in the Netherlands Antilles; associations with hypertension and diabetes mellitus

Waist circumference as a measurement of obesity in the Netherlands Antilles; associations with hypertension and diabetes mellitus

Fixation patterns, not clinical diagnosis, predict body size over‐estimation in eating disordered women and healthy controls

Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study

Contact Info

Product

Resources

About