Waist to hip ratio is a better predictor of esophageal acid exposure than body mass index

Abstract

WHR is a better predictor for esophageal acid exposure than BMI. Biomechanical and metabolic mechanisms of central fat distribution may influence reflux parameters in 24 hour pH impedance monitoring, which may affect patient selection for ambulatory reflux monitoring.

Dietary sugar and Barrett’s esophagus

“…In line with the findings of the study by Li et al., recent investigations revealed a positive correlation between GERD and lifestyle manifestations, i. e., obesity, central obesity, intake of carbohydrates [ 8 – 12 ]. Conceptually sugar consumption favors obesity, which in turn stresses the geometry of the anti-reflux mechanism within the lower end of the esophagus [ 1 , 4 , 5 ].…”

“…GERD represents a lifestyle problem and results from the consumption of large meals, increased amount of carbohydrate-containing foods and beverages, and lack of physical activity [ 1 – 3 , 8 – 12 ]. The study by Li et al.…”

“…Recent evidence highlights the association of GERD and BE with obesity and diet, i. e., sugar consumption [ 8 – 12 ]. Therefore, this paper aims to analyze recent data on the role of sugar intake for BE development.…”

Role of Overweight and Obesity in Gastrointestinal Disease

“…A recent study in which BMI, waist-hip-ratio (WHR), and GERD were compared, has pointed out that WHR is significantly associated with esophageal acid exposure and with impaired esophageal acid clearance concluding that WHR is a stronger predictor for pathological acid exposure at distal esophagus than BMI [23]. Despite anthropometric parameters, also body composition plays a pivotal role in the association between obesity and GERD.…”

Radiofrequency ablation in patients with large cervical heterotopic gastric mucosa and globus sensation: Closing the treatment gap

“…All patients had to indicate negative symptom correlation with reflux events to be included in this study. GERD was diagnosed when total percentage of pH <4 in the distal esophagus exceeded 4.2%, or when presence of reflux‐associated lesions was visible during endoscopy . Additionally, patients were screened for tumorous laryngeal lesions.…”