Wall-jet electrode in continuous monitoring voltammetry

Gunasingham, Hari; Fleet, B.

doi:10.1021/ac00259a050

Cited by 109 publications

(46 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A wall-jet-cell, providing low dead volume, fast response, good wash characteristics, ease of construction and compatibility with electrodes of various shapes and sizes, was used in flow determinations where a Perspex cup with axially positioned inlet polypropylene tubing is mounted at the sensing surface of the electrode body. 11,12 The optimized distance between nozzle and the sensing surface of the sensor was 5 mm; this provides the minimum thickness of the diffusion layer and consequently a fast response. Figure 1 represents the flow injection apparatus used in measurements.…”

Section: Apparatusmentioning

confidence: 99%

Application of Oxybutynin Selective Sensors for Monitoring the Dissolution Profile and Assay of Pharmaceutical Dosage Forms

Hamshary

Nashar

2010

ANAL. SCI.

View full text Add to dashboard Cite

Two ion-selective sensors of the plastic membrane type were prepared for the determination of oxybutynin hydrochloride (OxCl). They depend on the incorporation of the ion-associates with phosphotungestic acid or phosphomolybdic acid in a PVC matrix. A comparative study is made between their performance characteristics in batch and FIA conditions. The sensors have nearly the same usable concentration, temperature and pH range. They have a wide range of selectivity and can be applied for the determination of the relevant drug with nearly the same precision and accuracy in vitro. Dissolution testing was applied using the sensors; this offers a simple, rapid, cheap way out of sophisticated and high cost instruments used in the pharmacopeial method using HPLC. The investigated drug was determined in its pure and pharmaceutical preparations. The results were accurate and precise, as indicated by the recovery values and coefficients of variation.

show abstract

Section: Apparatusmentioning

confidence: 99%

Application of Oxybutynin Selective Sensors for Monitoring the Dissolution Profile and Assay of Pharmaceutical Dosage Forms

Hamshary

Nashar

2010

ANAL. SCI.

View full text Add to dashboard Cite

show abstract

“…25 The fast response of the electrode could be obtained by adjustment of the diffusion layer to minimum thickness and this can be achieved by optimizing the distance between the nozzle (a perspex cup with axially positioned inlet polypropeylene tubing which is mounted at the end of the membrane electrode) and the sensing surface of the electrode, the optimum thickness was 5 mm. 26,27 …”

Section: Optimization Of Fia Responsementioning

confidence: 99%

Flow Injection Analysis with Tubular Membrane Ion‐Selective Electrode and Coated Wires for Buspirone Hydrochloride

et al. 2006

View full text Add to dashboard Cite

Summary -New Plastic membrane ion-selective electrode for buspirone hydrochloride based on buspironium tetraphenylborate was prepared. The electrode exhibited mean slope of calibration graph of 58.4 mV per decade of BusCl concentration at 25°C. The electrode can be used within the concentration range 6.3 x10 -5 -10 -2 M BusCl at a pH range of 2.5-7.0. The standard electrode potentials were determined at different temperatures and used to calculate the isothermal temperature coefficient of the electrode, amounting to 0.00056 V°C -1 . The electrode showed a very good selectivity for BusCl with respect to a number of inorganic cations, sugars and amino acids. The electrode was applied to the potentiometric determination of the buspirone ion and its pharmaceutical preparation under batch and flow injection conditions. Also, buspirone was determined by conductimetric titrations. Graphite rod, copper and silver coated wire electrodes were prepared and characterized as sensors for the drug under investigation.

show abstract

“…As a compromise between sensitivity and reproducibility, a flow rate of 1.5 mL min À1 was selected for further studies. The limiting diffusion current i l corresponding to a walljet arrangement follows the equation [17] …”

Section: Influence Of the Flow-injection Variablesmentioning

confidence: 99%

Flow‐Injection Amperometric Detection with Solvent Polymeric Membrane Ion Sensors

2004

View full text Add to dashboard Cite

An amperometric detector for hydrophobic ions based on a plasticized poly(vinyl) chloride (PVC) membrane incorporated in a flow-injection system was developed. A four-electrode potentiostat with ohmic drop compensation was used, while a flow-through cell incorporated the four electrodes and the membrane, which contained tetrabutylammonium tetraphenylborate. When the influence of the applied potential and of the flow-injection variables on the determination of tetrabutylammonium was studied, a linear relationship was observed between current peak height and ion concentration over a range of 5 Â 10 À6 ± 6 Â 10 À5 M tetrabutylammonium. Good repeatability and between-day reproducibility and high sample frequency were obtained. The effect of other ions was studied. Two different amperometric methods, indirect and direct, were also developed for the determination of dodecylsulfate in the concentration range 3 Â 10 À5 ± 9 Â 10 À4 M.

show abstract

Wall-jet electrode in continuous monitoring voltammetry

Cited by 109 publications

References 18 publications

Application of Oxybutynin Selective Sensors for Monitoring the Dissolution Profile and Assay of Pharmaceutical Dosage Forms

Application of Oxybutynin Selective Sensors for Monitoring the Dissolution Profile and Assay of Pharmaceutical Dosage Forms

Flow Injection Analysis with Tubular Membrane Ion‐Selective Electrode and Coated Wires for Buspirone Hydrochloride

Flow‐Injection Amperometric Detection with Solvent Polymeric Membrane Ion Sensors

Contact Info

Product

Resources

About