Waon Therapy Improves Quality of Life as Well as Cardiac Function and Exercise Capacity in Patients With Chronic Heart Failure

Sobajima, Mitsuo; Nozawa, Takashi; Fukui, Yasutaka; Ihori, Hiroyuki; Ohori, Takashi; Fujii, Naohiko; Inoue, Hiroshi

doi:10.1536/ihj.14-266

Cited by 40 publications

(31 citation statements)

References 34 publications

(45 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This involves irradiating the entire body with FIR in a sauna ( Figure 1) at 60 °C for 15 minutes, followed by a further 30 minutes covered in blankets to cause an increase in core body temperature of around 1 °C. [2,3]. Localised FIR therapy is the other form, which typically consists of a device with ceramic plates which emit FIR irradiation when electrically heated.…”

Section: Introductionmentioning

confidence: 99%

Potential mechanisms for the effects of far-infrared on the cardiovascular system – a review

Shemilt

Bagabir

Lang

et al. 2019

Vasa

View full text Add to dashboard Cite

Abstract. Far-infrared (FIR) is a form of thermal radiation, which may have beneficial effects on cardiovascular health. Clinical studies suggest that FIR irradiation may have therapeutic effects in heart failure, myocardial ischaemia and may improve flow and survival of arteriovenous fistula. Animal studies have suggested a wide range of potential mechanisms involving endothelial nitric oxide synthase and nitric oxide bioavailability, oxidative stress, heat shock proteins and endothelial precursor cells. However, the exact cellular and molecular mechanism of FIR on the cardiovascular system remains elusive. The purpose of this review is to discuss the current literature, focusing on mechanistic studies involving the cardiovascular system, and with a view to highlighting areas for future investigation.

show abstract

Section: Introductionmentioning

confidence: 99%

Potential mechanisms for the effects of far-infrared on the cardiovascular system – a review

Shemilt

Bagabir

Lang

et al. 2019

Vasa

View full text Add to dashboard Cite

show abstract

“…1) Angiotensin-converting enzyme inhibitors and β-blockers are essential components of the treatment regimen for patients with chronic HF. Recently, nonpharmacological therapies, such as cardiac resynchronization therapy (CRT), 2) exercise therapy, 3) and Waon therapy 4) have also been used for the treatment of HF patients. Similarly, various other HF therapy regimens have been developed, and the field is dynamic and progressive.…”

mentioning

confidence: 99%

Utility of Nutritional Screening in Predicting Short-Term Prognosis of Heart Failure Patients

et al. 2018

View full text Add to dashboard Cite

SummaryControlling nutritional status (CONUT) uses 2 biochemical parameters (serum albumin and cholesterol level), and 1 immune parameter (total lymphocyte count) to assess nutritional status. This study examined if CONUT could predict the short-term prognosis of heart failure (HF) patients.A total of 482 (57.5%) HF patients from the Ibaraki Cardiovascular Assessment Study-HF (n = 838) were enrolled (298 men, 71.7 ± 13.6 years). Blood samples were collected at admission, and nutritional status was assessed using CONUT. CONUT scores were defined as follows: 0-1, normal; 2-4, light; 5-8, moderate; and 9-12, severe degree of undernutrition. Accordingly, 352 (73%) patients had light-to-severe nutritional disturbances. The logarithmically transformed plasma brain natriuretic peptide (log BNP) concentration was significantly higher in the moderate-severe nutritional disturbance group (2.92 ± 0.42) compared to the normal group (2.72 ± 0.45, P < 0.01). CONUT scores were significantly higher in the in-hospital death patients [4 (3-8), n = 14] compared with patients who were discharged following symptom alleviation [3 (1-5), n = 446, P < 0.05]. With the exception of transferred HF patients (n = 22), logistic regression analysis that incorporated the CONUT score and the log BNP, showed that a higher CONUT score (P = 0.019) and higher log BNP (P = 0.009) were predictors of in-hospital death, and the median duration of hospital stay was 20 days.Our results demonstrate the usefulness of CONUT scores as predictors of short-term prognosis in hospitalized HF patients.(Int Heart J Advance Publication)

show abstract

“…Brachial artery diameter was measured by B-mode ultrasound imaging (UNEX EF 18G, UNEX Co., Aichi, Japan) with a 7.5-MHz linear artery transducer while an elctrocardiogram was simultaneously recorded. 12,13) The right brachial artery was scanned in longitudinal sections 1~10 cm above the elbow after at least 5 minutes of rest in a supine position; the skin surface was marked, and the arm was kept in the same position during the study. After baseline measurement of the brachial artery diameter (average of 10 times measurements), FMD was determined by scans during reactive hyperemia.…”

Section: Study Subjects and Protocolsmentioning

confidence: 99%

Oral Administration of Glucosamine Improves Vascular Endothelial Function by Modulating Intracellular Redox State

et al. 2017

View full text Add to dashboard Cite

SummaryGlucosamine, used to treat osteoarthritis, has been shown to have anti-inflammatory and antiatherosclerotic effects in experimental studies. A recent cohort study has demonstrated that the use of glucosamine was significantly associated with decreased total mortality. Vascular endothelial function is a potent surrogate marker of atherosclerosis and cardiovascular mortality where oxidative stress could participate. Therefore, we investigated whether glucosamine improves vascular endothelial function and intracellular redox state. We examined the effects of oral glucosamine administration (3000 mg/day) for 4 weeks on flow-mediated vasodilation (FMD) and intraerythrocyte glutathione parameters in 20 volunteers. Nineteen age-matched volunteers served as controls. Glucosamine administration significantly increased FMD (from 7.0 ± 2.3 to 8.7 ± 2.3%, P = 0.022). In the control group, FMD did not change. Glucosamine administration significantly increased intraerythrocyte total glutathione levels (from 212.9 ± 46.2 to 240.6 ± 49.4 μmol/L, P = 0.006), intraerythrocyte reduced form of glutathione (GSH) levels (from 124.7 ± 42.6 to 155.2 ± 47.7 μmol/L; P = 0.004) and intraerythrocyte GSH/oxidized form of glutathione (GSSG) ratios (from 3.18 ± 1.64 to 3.88 ± 1.61, P = 0.04). In the control group, any glutathione parameters did not change. Moreover, a stepwise multivariate analysis revealed percent change of GSH/GSSG is the only independent predictor for those of FMD (standardized β = 0.58, P = 0.007) in the glucosamine group. Glucosamine administration improved FMD in association with amelioration of intraerythrocyte GSH/GSSG ratios. These results suggest that oral glucosamine administration might improve vascular endothelial function by modulating intracellular redox state. (Int Heart J 2017; 58: 926-932)

show abstract

Waon Therapy Improves Quality of Life as Well as Cardiac Function and Exercise Capacity in Patients With Chronic Heart Failure

Cited by 40 publications

References 34 publications

Potential mechanisms for the effects of far-infrared on the cardiovascular system – a review

Potential mechanisms for the effects of far-infrared on the cardiovascular system – a review

Utility of Nutritional Screening in Predicting Short-Term Prognosis of Heart Failure Patients

Oral Administration of Glucosamine Improves Vascular Endothelial Function by Modulating Intracellular Redox State

Contact Info

Product

Resources

About