“…Based on the different R and R′ groups, the cyclic terpene acid moiety in shellac can be divided into shellolic, jalaric, laccijalaric, laksholic, laccishellolic, and laccilaksholic acids . With more than 4000 years of practical history, shellac has been widely used in various fields, including metallurgy, dyeing, food, and medicine. , Initially, unbleached shellac, which also contains special pigments, was mainly used in silk dyeing and to coat artworks, metal devices, and military products owing to its good ductility, insulation, adhesion, and barrier properties. , Shellac has also been proven to be nontoxic and edible, as confirmed by its wide application as a food-grade coating and wax. , In recent decades, shellac has been used to develop delivery systems, , owing to its several advantages including recognized safety, colonic pH responsiveness, well film-forming properties, easy reactivity, special solubility, and amphiphilicity, which will be further described in detail later in this review.…”