P akistan is the world's fourth-highest water user and ranks third amongst countries facing water shortages, as reported by the International Monetary Fund (IMF) (Ahmad, 2021). With the increase in overall water use, wastewater production and pollution load are also continuously increasing in Pakistan (Connor et al., 2017). In Pakistan, approximately half of the two million wet tonnes of human waste produced each year end up polluting the water (Maqbool, 2022). A study found that 60 Abstract | Wastewater production and disposal have become issues of concern with the growing population and increase in overall water usage. About 4.36 billion m 3 (BCM) of wastewater is generated every year in Pakistan and not even 1% of the total wastewater gets treated before its disposal. The reported research aims to assess the concentration of contaminants in wastewater. Samples of wastewater were collected from Wali Muhammad Canal, Multan, and analyzed for heavy metals (HMs) including cadmium (Cd), copper (Cu), nickle (Ni), and zinc (Zn), along with basic physicochemical parameters including biological oxygen demand (BOD), chemical oxygen demand (COD), pH, electrical conductivity (EC), total solids (TS), total suspended solids (TSS), total dissolved solids (TDS), sodium (Na), calcium (Ca), potassium (K), magnesium (Mg), residual sodium carbonates (RSC), sodium adsorption ratio (SAR), carbonates (CO 3 ), and bicarbonates (HCO 3 ) by using standard analytical procedures. The contamination in the wastewater includes temperature,