Water-equivalence of gel dosimeters for radiology medical imaging

Valente, M.; Vedelago, José; Chacón, D.; Mattea, Facundo; Velásquez, J.; Pérez, Pedro

doi:10.1016/j.apradiso.2018.03.005

Cited by 25 publications

(9 citation statements)

References 16 publications

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“…A recent study for radiology usage analyzed the water-equivalence properties of Fricke (cheaper and easier gel dosimeter method) and three different polymer gel dosimeters. Each of the polymer applications in gel dosimeters like IA, N-isopropyl acrylamide, and polyacrylamide presented the same linear trend at a dose-response curve, as well as a raised intensity in water-equivalence [169].…”

Section: Major Applications Of Iamentioning

confidence: 99%

Biomass-Derived Production of Itaconic Acid as a Building Block in Specialty Polymers

2019

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Biomass, the only source of renewable organic carbon on Earth, offers an efficient substrate for bio-based organic acid production as an alternative to the leading petrochemical industry based on non-renewable resources. Itaconic acid (IA) is one of the most important organic acids that can be obtained from lignocellulose biomass. IA, a 5-C dicarboxylic acid, is a promising platform chemical with extensive applications; therefore, it is included in the top 12 building block chemicals by the US Department of Energy. Biotechnologically, IA production can take place through fermentation with fungi like Aspergillus terreus and Ustilago maydis strains or with metabolically engineered bacteria like Escherichia coli and Corynebacterium glutamicum. Bio-based IA represents a feasible substitute for petrochemically produced acrylic acid, paints, varnishes, biodegradable polymers, and other different organic compounds. IA and its derivatives, due to their trifunctional structure, support the synthesis of a wide range of innovative polymers through crosslinking, with applications in special hydrogels for water decontamination, targeted drug delivery (especially in cancer treatment), smart nanohydrogels in food applications, coatings, and elastomers. The present review summarizes the latest research regarding major IA production pathways, metabolic engineering procedures, and the synthesis and applications of novel polymeric materials.

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Section: Major Applications Of Iamentioning

confidence: 99%

Biomass-Derived Production of Itaconic Acid as a Building Block in Specialty Polymers

2019

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“…The output of most gel dosimeters does not depend significantly on the radiation quality when considering high-energy photon and electron radiotherapy beams [ 7 , 88 ] due to the similar LET in the MeV energy range for these particles [ 97 ]. However, dedicated preliminary characterization is required to use gel dosimetry for applications with non-negligible LET differences compared with typical radiotherapy radiation qualities, as occurs for brachytherapy [ 98 , 99 , 100 ] and radiology [ 14 , 101 , 102 ]. In order to avoid systematic errors in the dose distribution assessment for low-energy applications, the corresponding gel dosimeter dose–response output needs to be obtained for the specific beam quality, and the relative performance to the reference quality ( 60 Co) may serve to correlate with their application in the MeV range.…”

Section: Operational Properties Of Gel Dosimetrymentioning

confidence: 99%

Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review

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Strumia

et al. 2022

Gels

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Advances in radiotherapy technology during the last 25 years have significantly improved both dose conformation to tumors and the preservation of healthy tissues, achieving almost real-time feedback by means of high-precision treatments and theranostics. Owing to this, developing high-performance systems capable of coping with the challenging requirements of modern ionizing radiation is a key issue to overcome the limitations of traditional dosimeters. In this regard, a deep understanding of the physicochemical basis of gel dosimetry, as one of the most promising tools for the evaluation of 3D high-spatial-resolution dose distributions, represents the starting point for developing new and innovative systems. This review aims to contribute thorough descriptions of the chemical processes and interactions that condition gel dosimetry outputs, often phenomenologically addressed, and particularly formulations reported since 2017.

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“…Effective mass absorption coefficients have been assessed for the different compound materials of endodontic relevance within the μCT samples using the additivity rule, 17,18 thus, obtaining photon mass absorption for the gutta-percha cone, 3 human dentine, 18 and a generalized bioceramics formulation, 5,19,20 by means of summing the atomic photon mass absorption coefficient of the elements 21 in the compounds according to their corresponding fraction by weight, as reported in Table 2. Within this framework, the photon mass absorption coefficient evaluated at the corresponding energy ( μ ρ h i E ð Þ) has been calculated for the materials relevant in the endodontic samples.…”

Section: Absorption Contrast Imagingmentioning

confidence: 99%

Adaptation of a microCT facility for automatic recognition of bioceramic‐based sealers in molar root canals aimed at endodontic treatment quality control

et al. 2021

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Computed tomography (CT) technology has seen tremendous growth since its first medical applications in the early 1970s. Nowadays, high-spatial-resolution digital detectors enable the micro-computed tomography (μCT) technique, which has been introduced to a wide variety of applications, including biomedical sciences like odontological applications. Endodontic treatments stand as one of the most common dental procedures, and the quality of the treatment is essential to prevent and control any potential infection of root canals. This treatment is typically achieved by careful cleaning, shaping, and sealing steps.Often, endodontic treatments fail due to a poor seal, even if a meticulous root canal preparation is carried out. The present work reports on the spectrometric adaptation of a μCT facility for accurate quantification of root canal sealing with bioceramics, aimed at assessing the sealing performance of the new Bio-C Sealer product. A dedicated irradiation setup along with digital image processing techniques have been developed for the accurate and automatic recognition of dental samples root canal anatomy and bioceramic-based sealers. The performance of the proposed approaches has proved to be qualitatively and quantitatively robust for automatic characterization of the endodontic treatment sealing quality, satisfactorily identifying and segmenting canal root, gutta-percha cone, and bioceramics.

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Water-equivalence of gel dosimeters for radiology medical imaging

Cited by 25 publications

References 16 publications

Biomass-Derived Production of Itaconic Acid as a Building Block in Specialty Polymers

Biomass-Derived Production of Itaconic Acid as a Building Block in Specialty Polymers

Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review

Adaptation of a microCT facility for automatic recognition of bioceramic‐based sealers in molar root canals aimed at endodontic treatment quality control

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