Water exposure assessment of aryl hydrocarbon receptor agonists in Three Gorges Reservoir, China using SPMD-based virtual organisms

Wang, Jingxian; Bernhöft, Silke; Pfister, Gerd; Schramm, Karl‐Werner

doi:10.1016/j.scitotenv.2014.07.015

Cited by 3 publications

(2 citation statements)

References 54 publications

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“…This results in lower concentrations of contaminants downstream of Chongqing, which is in agreement with previous findings. 2, 56 The artificial Hanfeng Lake at Kaixian exhibited the highest AhR-mediated activity, which could be attributed to a lower dilution of discharged contamination compared to the Chongqing area, and a potential accumulation of contamination in the lake. 2 Target Chemical Analysis.…”

Section: ■ Results and Discussionmentioning

confidence: 98%

“…Thus, higher levels of contamination in the upstream of Yangtze river at Chongqing area may be diluted by sediments of the less contaminated tributary, the Jialing River. This results in lower concentrations of contaminants downstream of Chongqing, which is in agreement with previous findings. , The artificial Hanfeng Lake at Kaixian exhibited the highest AhR-mediated activity, which could be attributed to a lower dilution of discharged contamination compared to the Chongqing area, and a potential accumulation of contamination in the lake …”

Section: Resultsmentioning

confidence: 99%

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Effect-Directed Analysis of Aryl Hydrocarbon Receptor Agonists in Sediments from the Three Gorges Reservoir, China

Xiao

Krauß

Floehr

et al. 2016

Environ. Sci. Technol.

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The construction of the Three Gorges Dam (TGD) in the Yangtze River raises great concern in ecotoxicological research since large amounts of pollutants enter the Three Gorges Reservoir (TGR) water bodies after TGD impoundment. In this work, effect-directed analysis (EDA), combining effect assessment, fractionation procedure, and target and nontarget analyses, was used to characterize aryl hydrocarbon receptor (AhR) agonists in sediments of the TGR. Priority polycyclic aromatic hydrocarbons (PAHs) containing four to five aromatic rings were found to contribute significantly to the overall observed effects in the area of Chongqing. The relatively high potency fractions in the Kaixian area were characterized by PAHs and methylated derivatives thereof and heterocyclic polycyclic aromatic compounds (PACs) such as dinaphthofurans. Benzothiazole and derivatives were identified as possible AhR agonists in the Kaixian area based on nontarget liquid chromatography-high resolution mass spectrometry (LC-HRMS). To our knowledge, this study is the first one applying the EDA approach and identifying potential AhR agonists in TGR.

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Section: ■ Results and Discussionmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Effect-Directed Analysis of Aryl Hydrocarbon Receptor Agonists in Sediments from the Three Gorges Reservoir, China

Xiao

Krauß

Floehr

et al. 2016

Environ. Sci. Technol.

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Depth profile of persistent and emerging organic pollutants upstream of the Three Gorges Dam gathered in 2012/2013

Deyerling

Wang

et al. 2015

Environ Sci Pollut Res

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Persistent and emerging organic pollutants were sampled in September 2012 and 2013 at a sampling site in front of the Three Gorges Dam near Maoping (China) in a water depth between 11 and 61 m to generate a depth profile of analytes. A novel compact water sampling system with self-packed glass cartridges was employed for the on-site enrichment of approximately 300 L of water per sample to enable the detection of low analytes levels in the picogram per liter-scale in the large water body. The overall performance of the sampling system was acceptable for the qualitative detection of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), perfluoroalkylic acids (PFAAs), pharmaceutical residues and polar pesticides. Strongly particle-associated analytes like PAHs and PCBs resided mainly in the glass wool filter of the sampling system, whereas all other compounds have mainly been enriched on the XAD-resin of the selfpacked glass cartridges. The sampling results revealed qualitative information on the presence, depth distribution and origin of the investigated compounds. Although the depth profile of PAHs, PCBs, OCPs, and PFAAs appeared to be homogeneous, pharmaceuticals and polar pesticides were detected in distinct different patterns with water depth. Source analysis with diagnostic ratios for PAHs revealed their origin to be pyrogenic (burning of coal, wood and grass). In contrast, most PCBs and OCPs had to be regarded as legacy pollutants which have been released into the environment in former times and still remain present due to their persistence. The abundance of emerging organic pollutants could be confirmed, and their most abundant compounds could be identified as perfluorooctanoic acid, diclofenac and atrazine among investigated PFAAs, pharmaceuticals and polar pesticides, respectively.

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Diverse toxicological risks of PAHs in surface water with an impounding level of 175 m in the Three Gorges Reservoir Area, China

Tang

Junaid

Niu

et al. 2017

Science of The Total Environment

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Water exposure assessment of aryl hydrocarbon receptor agonists in Three Gorges Reservoir, China using SPMD-based virtual organisms

Cited by 3 publications

References 54 publications

Effect-Directed Analysis of Aryl Hydrocarbon Receptor Agonists in Sediments from the Three Gorges Reservoir, China

Effect-Directed Analysis of Aryl Hydrocarbon Receptor Agonists in Sediments from the Three Gorges Reservoir, China

Depth profile of persistent and emerging organic pollutants upstream of the Three Gorges Dam gathered in 2012/2013

Diverse toxicological risks of PAHs in surface water with an impounding level of 175 m in the Three Gorges Reservoir Area, China

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