Water soluble complexes of curcumin with cyclodextrins: Characterization by FT-Raman spectroscopy

Improvement of Solubility and Antifungal Activity of a New Aminothiophene Derivative by Complexation with 2-Hydroxypropyl-β-cyclodextrin

“…Such attenuation of signal intensity was previously connected to a reduction of electron molecular polarizability within the complex probably due the interactions between the compound and CD. 32,33 Similar to the results obtained in the FTIR spectra, no spectral Improvement of Solubility and Antifungal Activity of a New Aminothiophene Derivative J. Braz. Chem.…”

“…[30][31][32][33] This technique presents a clear advantage when compared to the analogous FTIR spectra due to the relative silence of the cyclodextrin in the Raman spectra, which does not show any relevant overlap in the spectral patterns, permitting a better comparison between the free and the included molecule. 34 Raman spectra showed a decrease in the peak intensity in the 6CN10:HP-β-CD complex when compared with the 6CN10 and with the 6CN10 and HP-β-CD physical mixture spectra (Figure 4).…”

Curcumin-Hydroxypropyl-β-Cyclodextrin Inclusion Complex Preparation Methods: Effect of Common Solvent Evaporation, Freeze Drying, and pH Shift on Solubility and Stability of Curcumin

“…The temperature was controlled at 37 ± 0.5 o C and the paddle was set at 75 rpm throughout the study. At fixed time intervals (3,6,10,15,30,45, and 60 min), 2 mL aliquots were withdrawn and equal volumes of fresh medium were replaced. The samples were filtered, suitably diluted, and assayed for curcumin content by using UV-visible spectroscopy at 430 nm as described in the section "Quantitation of curcumin".…”

“…For curcumin, it is not yet clear which type of CD would be the best choice to fit with the curcumin molecule. Previous publications have often used β-and γ-CD and their hydroxypropyl derivatives to prepare inclusion complexes with curcumin [7][8][9][10].…”

Investigating the use of curcumin-loaded electrospun filaments for soft tissue repair applications

“…Characteristic bands of pure curcumin (see Figure S1) are observed at 3,510 cm −1 (O-H stretching of the phenol group), 1,599 cm −1 (aromatic C=C stretching), and 1,501 cm −1 (C=O stretching, C-C=O bending). 36 The main characteristic bands of pure PDO ( Figure 3C, Curve a) are observed at 2,927 cm −1 (C-H stretching), 1,734 cm −1 (C=O stretching of ester groups), and 1,429 cm −1 (C-H bending). 37 After incorporation of curcumin in PDO, the typical O-H absorption bands of curcumin were not observed in the filament spectra spectrum.…”