Water-Soluble Vitamins in Protein-Calorie Malnutrition

Thanangkul, Ousa

doi:10.1016/b978-0-12-526150-0.50022-9

Cited by 2 publications

(2 citation statements)

References 31 publications

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“…may overshadow, alter or substitute for the classical manifestation of B complex vitamin deficiencies. Our findings show that children with PCM have depressed stores of both water-soluble and fat-soluble vitamins (25). All children should be supplemented with all vitamins, not only to resaturate the shrunken tissue but also to provide adequate amounts for the proper functioning of new tissue generated during growth.…”

Section: Clinical and Laboratory Findingsmentioning

confidence: 75%

“…Clinical evidence of thiamine deficiency (such as hoarseness, peripheral neurop athy, and/or congestive heart failure) is rare, whereas the clinical signs of riboflavin deficiency (as shown by glossitis, nasolabial seborrhea, and angular stomatitis) are common. But the clinical signs of these two vitamin deficiencies are deceptive because there is little correlation between the clinical signs and the biochemical findings (25). Vitamin D deficiency was not common among the PCM children seen at this Center.…”

Section: Clinical and Laboratory Findingsmentioning

confidence: 91%

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Clinical aspects of protein deficiency with special reference to protein calorie malnutrition (PCM) in children.

Thanangkul

Damrongsak

Vithayasai

et al. 1980

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

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Section: Clinical and Laboratory Findingsmentioning

confidence: 75%

Section: Clinical and Laboratory Findingsmentioning

confidence: 91%

Clinical aspects of protein deficiency with special reference to protein calorie malnutrition (PCM) in children.

Thanangkul

Damrongsak

Vithayasai

et al. 1980

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

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Nerve fibre degeneration of the central and peripheral nervous systems in severe protein deprivation in rats

Oldfors

1981

Acta Neuropathol

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Knowledge from previous reports that kwashiorkor in man may lead to nerve fibre degeneration prompted this study on rats. The rats were subjected to severe protein deprivation from 6 weeks of age. Protein deprivation was achieved by feeding the rats ad lib with a diet containing only 1.5% protein. Control rats received an iso-caloric diet with 14% protein. The vitamin content in both diets was well above normal requirements. In relation to body weight the protein-deprived rats did not consume less food than the control rats. Protein deprivation resulted in stunted body growth, markedly reduced values of serum albumin, and changes in the fur accompanied by areas of alopecia. Furthermore, the protein-deprived rats showed degeneration of nerve fibres in the medial parts of the posterior columns of the cervical but not the sacral part of the spinal cord and nerve fibre degeneration in the distal but not the proximal parts of the longitudinal tail nerves. Teased nerve fibre preparations of the tail nerves revealed changes consistent with the Wallerian type of degeneration. It is concluded that severe protein deprivation in young rats may lead to a "dying-back" type of neuropathy in the central and peripheral nervous systems.

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Water-Soluble Vitamins in Protein-Calorie Malnutrition

Cited by 2 publications

References 31 publications

Clinical aspects of protein deficiency with special reference to protein calorie malnutrition (PCM) in children.

Clinical aspects of protein deficiency with special reference to protein calorie malnutrition (PCM) in children.

Nerve fibre degeneration of the central and peripheral nervous systems in severe protein deprivation in rats

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