2021
DOI: 10.2139/ssrn.3765793
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'We Are Not Guinea Pigs': The Effects of Negative News on Vaccine Compliance

Abstract: In 1996, following an epidemic, Pfizer tested a new drug on 200 children in Muslim Nigeria. 11 children died and multiple were disabled. We study the effects of negative news on vaccine compliance using evidence from the 2000 disclosure of deaths of Muslim children in the Pfizer trials. Muslim mothers reduced routine vaccination of children born after the 2000 disclosure. The effect was stronger for educated mothers and mothers residing in minority Muslim neighborhoods with relatively stronger ties to religiou… Show more

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Cited by 9 publications
(9 citation statements)
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“…Secondly, we contribute to the sparse literature that generates causal evidence about what underpins the acceptance of vaccines in LICs and LMICs, being among one of the first experiments to explicitly focus on COVID-19 vaccines. Seminal studies prior to the COVID-19 pandemic have tended to focus on how mistrust towards vaccines was influenced by questionable activities being brought to light (Archibong and Annan, 2021;Martinez-Bravo and Stegmann, 2022). Since the outset of the pandemic there has been some experimental work in high-income countries about ways to boost COVID-19 vaccine acceptance (e.g., Kaplan and Milstein, 2021), but in LICs and LMICs existing publicly available studies have been almost exclusively descriptive (e.g., Kanyanda et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…Secondly, we contribute to the sparse literature that generates causal evidence about what underpins the acceptance of vaccines in LICs and LMICs, being among one of the first experiments to explicitly focus on COVID-19 vaccines. Seminal studies prior to the COVID-19 pandemic have tended to focus on how mistrust towards vaccines was influenced by questionable activities being brought to light (Archibong and Annan, 2021;Martinez-Bravo and Stegmann, 2022). Since the outset of the pandemic there has been some experimental work in high-income countries about ways to boost COVID-19 vaccine acceptance (e.g., Kaplan and Milstein, 2021), but in LICs and LMICs existing publicly available studies have been almost exclusively descriptive (e.g., Kanyanda et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…There is anecdotal evidence and media reports of distrust of pharmaceutical companies in LMICs, including concerns that people in such countries could be used as "guinea pigs" to pilot-test vaccines not yet approved for use elsewhere in high-income countries. [84][85][86][87] For example, in Nigeria, there are reported cases of child and infant deaths and disabilities following the administration of an experimental drug during a meningitis outbreak. 88 Such events create unprecedented adverse experiences that could hinder vaccine uptake and the understanding of clinical research to test new vaccines.…”
Section: Distrust In Pharmaceutical Companiesmentioning
confidence: 99%
“…For another thing, vaccine compliance is strongly influenced by the environment, that is, where and when this individual decision is taken. For example, Archibong and Annan (2021), A. Banerjee et al (2021), Hansen and Schmidtblaicher (2021), Lowes and Montero (2021), and Martinez‐Bravo and Stegmann (2021) document that propaganda, the authority's miscommunication, medical malpractice, or the campaign design have strong effects on vaccine compliance. Simply regressing economic insecurity on the individual decision of getting the COVID‐19 vaccine will therefore lead to a biased estimation due to an underlying endogeneity problem.…”
Section: Empirical Strategymentioning
confidence: 99%