Wearable hollow microneedle sensing patches for the transdermal electrochemical monitoring of glucose

Parrilla, Marc; Detamornrat, Usanee; Domínguez-Robles, Juan; Donnelly, Ryan F.; Wael, Karolien De

doi:10.1016/j.talanta.2022.123695

Cited by 79 publications

(53 citation statements)

References 48 publications

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“…However, the basic functions of nanomaterials in biosensors are aiding biomolecule immobilization and labelling, catalysis of electrochemical reactions, increasing the electron transfer rate, and acting as the reactant [ 32 ]. The most commonly used nanomaterials are metal [ 69 , 70 , 71 ], carbon-based [ 72 , 73 ], and metal oxide [ 74 , 75 , 76 ].…”

Section: Generation Of Glucose Biosensormentioning

confidence: 99%

Progress of Enzymatic and Non-Enzymatic Electrochemical Glucose Biosensor Based on Nanomaterial-Modified Electrode

2022

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This review covers the progress of nanomaterial-modified electrodes for enzymatic and non-enzymatic glucose biosensors. Fundamental insights into glucose biosensor components and the crucial factors controlling the electrochemical performance of glucose biosensors are discussed in detail. The metal, metal oxide, and hybrid/composite nanomaterial fabrication strategies for the modification of electrodes, mechanism of detection, and significance of the nanomaterials toward the electrochemical performance of enzymatic and non-enzymatic glucose biosensors are compared and comprehensively reviewed. This review aims to provide readers with an overview and underlying concept of producing a reliable, stable, cost-effective, and excellent electrochemical performance of a glucose biosensor.

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Section: Generation Of Glucose Biosensormentioning

confidence: 99%

Progress of Enzymatic and Non-Enzymatic Electrochemical Glucose Biosensor Based on Nanomaterial-Modified Electrode

2022

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“…In particular, sweat sampling methods using microneedles involve transdermal electro-osmosis penetration and the extraction of target analytes by a porous microneedle. In the initial procedure, a specific drug is applied to the skin for transdermal injection, delivered to the body over time with a microneedle injected into the target body [ 159 ]. It then creates a large capillary pressure, quickly drawing interstitial fluid from the body.…”

Section: Sweat-sensing Device (Ssd)mentioning

confidence: 99%

“…( c ) Scheme layout of microneedle array component in a single SSD. Reprinted from [ 159 ], copyright (2019), with permission from Elsevier.…”

Section: Figurementioning

confidence: 99%

A Comprehensive Review of the Recent Developments in Wearable Sweat-Sensing Devices

Ibrahim

Sabani

Johari

et al. 2022

Sensors

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Sweat analysis offers non-invasive real-time on-body measurement for wearable sensors. However, there are still gaps in current developed sweat-sensing devices (SSDs) regarding the concerns of mixing fresh and old sweat and real-time measurement, which are the requirements to ensure accurate the measurement of wearable devices. This review paper discusses these limitations by aiding model designs, features, performance, and the device operation for exploring the SSDs used in different sweat collection tools, focusing on continuous and non-continuous flow sweat analysis. In addition, the paper also comprehensively presents various sweat biomarkers that have been explored by earlier works in order to broaden the use of non-invasive sweat samples in healthcare and related applications. This work also discusses the target analyte’s response mechanism for different sweat compositions, categories of sweat collection devices, and recent advances in SSDs regarding optimal design, functionality, and performance.

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“…In addition, it also creates new research directions for drug delivery, real-time monitoring, wearable electronic devices, and other fields. In addition, although there have been many research reports on electrochemical microneedles [ 28 ], there is still a lack of comprehensive introduction. In this review, we have provided a comprehensive overview of this field and summarized some of the work of electrochemical biosensors over the past two years [ 29 ], including the preparation methods and materials of electrochemical microneedles, their application in the medical field, the monitoring of biomarkers, and future development directions [ 30 ], as shown in Figure 1 .…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Microneedles: Innovative Instruments in Health Care

2022

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As a significant part of drug therapy, the mode of drug transport has attracted worldwide attention. Efficient drug delivery methods not only markedly improve the drug absorption rate, but also reduce the risk of infection. Recently, microneedles have combined the advantages of subcutaneous injection administration and transdermal patch administration, which is not only painless, but also has high drug absorption efficiency. In addition, microneedle-based electrochemical sensors have unique capabilities for continuous health state monitoring, playing a crucial role in the real-time monitoring of various patient physiological indicators. Therefore, they are commonly applied in both laboratories and hospitals. There are a variety of reports regarding electrochemical microneedles; however, the comprehensive introduction of new electrochemical microneedles is still rare. Herein, significant work on electrochemical microneedles over the past two years is summarized, and the main challenges faced by electrochemical microneedles and future development directions are proposed.

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Wearable hollow microneedle sensing patches for the transdermal electrochemical monitoring of glucose

Cited by 79 publications

References 48 publications

Progress of Enzymatic and Non-Enzymatic Electrochemical Glucose Biosensor Based on Nanomaterial-Modified Electrode

Progress of Enzymatic and Non-Enzymatic Electrochemical Glucose Biosensor Based on Nanomaterial-Modified Electrode

A Comprehensive Review of the Recent Developments in Wearable Sweat-Sensing Devices

Electrochemical Microneedles: Innovative Instruments in Health Care

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