This article both introduces our Special Issue on “Zooarchaeology and Human Ecodynamics in East Polynesia” and reviews recent research from East Polynesia at large. The seven articles and discussion essay derive from a symposium at the 14th International Council for Archaeozoology (ICAZ) conference in Cairns, Australia (2023). To contextualize these contributions, we review recent studies (2016–2024) from the region relating to human–animal relationships, including morphological, ancient DNA, and stable isotope research. Seven areas or themes emerge from our review, representing substantive, analytical and technical domains. These include (1) geographic coverage; (2) methodological issues; (3) assessments of anthropogenic impacts; (4) studies of domestic and commensal taxa; (5) animals in social, ritual and symbolic roles; (6) engagement with historical records and traditional ecological knowledges (TEK); and (7) emerging technologies. We conclude with a brief summary of recent achievements and propose future directions for zooarchaeological studies in East Polynesia and the wider Pacific.