This study aimed to explore a methodology for the professional teaching of students of technological institutes (whether it is middle and/or higher level) in inverted classrooms. It is based on the alternative and interactive method of content appropriation based on projects, which integrate the face-to-face modality with the virtual modality. The scientific novelty lies in the establishment of a dynamic that integrates the face-to-face modality with the virtual modality, based on the link between academic, labor, and research. Document review methods, the system approach, direct observation in the field, the pedagogical pre-experiment, and the Chi-square statistical test (X2) are used. As a result, the favorable impacts on the development of professional skills were observed in a sample of 100 students of the Mechanics career at the University of Holguín, Cuba, with the application of the result. It can be generalized in any worker training center with flexibility and adaptability to the characteristics of these entities.