Weight loss and weight loss maintenance efficacy of a novel weight loss program: The retrospective RNPC® cohort

Thorning, Tanja Kongerslev; Fabre, Odile; Legrand, Rémy; Astrup, Arne; Hjorth, Mads F.

doi:10.1016/j.obmed.2018.05.001

Cited by 10 publications

(9 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The CO-RNPC study was a prospective multicentre cohort conducted in the RNPC ® centres in France ( n = 79; Figure 1 ). The weight loss program has been extensively presented elsewhere [ 18 ]. Briefly, the RNPC ® program (for Rééducation Nutritionnelle Psycho-Comportementale, i.e., Nutritional Psycho-Behavioural Rehabilitation) is a three-stage weight loss program performed in 79 centres distributed across France.…”

Section: Methodsmentioning

confidence: 99%

“…This unprecedented context has accelerated the development of remote consultations to ensure adherence to the proposed weight loss program and to maintain weight loss trajectories. The RNPC ® nationwide program (79 centres for Rééducation Nutritionnelle Psycho-Comportementale, i.e., Nutritional Psycho-Behavioural Rehabilitation) [ 18 ] was prospectively evaluated in terms of weight loss and body composition changes before, during, and after LD.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Impact of the COVID-19 Lockdown on Weight Loss and Body Composition in Subjects with Overweight and Obesity Participating in a Nationwide Weight-Loss Program: Impact of a Remote Consultation Follow-Up—The CO-RNPC Study

et al. 2021

Self Cite

View full text Add to dashboard Cite

The aim of this study was to assess the impact of the nationwide total lockdown (LD) in France on weight loss and body composition modifications in subjects participating in a weight loss program and to evaluate the impact of remote consultations on participants’ adherence to the weight loss program. The CO-RNPC study was a prospective multicentre cohort study including participants undergoing a two to six months program. The rate of weight loss in kg/week was computed before (15 days), during (99 days) and after LD (15 days). In the 1550 completing participants, body weight decreased from 87.1 kg [IQR 77.0; 100.2] to 82.3 kg [72.1; 94.3] resulting in a difference of −4.79 kg [−4.48; −5.10] (p < 0.01), with a corresponding reduction in waist circumference by 4 cm ([0; 9], p < 0.01). The median weight loss was 4.4 kg [0.5; 9.4] in those who used remote consultations, and 1.4 kg [0.8; 5.7] in the no remote consultation group (p < 0.01). In this large prospective cohort, we observed that the rate of weight loss was reduced during LD. This reduction was counterbalanced in participants involved in a remote consultation follow-up with a dose-effect response based on the number of remote consultations.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Impact of the COVID-19 Lockdown on Weight Loss and Body Composition in Subjects with Overweight and Obesity Participating in a Nationwide Weight-Loss Program: Impact of a Remote Consultation Follow-Up—The CO-RNPC Study

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…This was a retrospective study from the French RNPC© program, which has already been described elsewhere [12]. Briefly, RNPC© is a three-phase dietary program carried out in 76 French centers, its specificity being a special emphasis on long-term maintenance of the achieved weight loss thanks to a close follow-up by dieticians (twice a month).…”

Section: Rnpc© Programmentioning

confidence: 99%

“…The duration of each phase was variable, depending on how quickly patients reached their personal objective of weight. According to Thorning et al [12], the median duration of the weight loss phase was 111 days (IQR: 57; 182) in women and 92 days (IQR: 48; 157) in men. The median for the full program was 258 days (IQR: 196; 362) for women and 230 days (IQR: 167; 318) for men.…”

Section: Rnpc© Programmentioning

confidence: 99%

“…RNPC© (for Rééducation Nutritionnelle et Psycho-Comportementale, i.e., the Nutritional Psycho-Behavioral Reeducation) program, based on a high-protein, low-carbohydrate, and low-fat diet, has already proven to be an efficient [6] and cost-effective [12] weight loss intervention with significant improvement in metabolic parameters following its weight loss phase [13]. The main objective of this study was to assess whether the RNPC© program is associated with a modification of patients' Modification of Diet in Renal Disease (MDRD) equation-based estimated glomerular filtration rate (eGFR) during the program high-protein phases, i.e., weight loss and early stabilization phases.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Specific High-Protein Weight Loss Program Does Not Impair Renal Function in Patients Who Are Overweight/Obese

et al. 2022

Self Cite

View full text Add to dashboard Cite

Although high-protein diets appear to be the most efficient way to lose weight, concerns may arise about their innocuity on renal function. The objective of this study is to assess the impact of a weight loss program on renal function. A multicentric cohort-based study was performed using the RNPC© French national weight loss program. Patients with at least two creatinine measurements at the beginning of the program and at the end of the weight loss phase between 1 January 2016 and 1 July 2021 were included. Renal function was assessed by Modification of Diet in Renal Disease (MDRD) equation-based estimated glomerular filtration rate (eGFR). From 4394 patients with two creatinine measurements included, 1579 (35.9%) had normal eGFR (MDRD 90–120 mL/min/1.73 m2), 210 (4.8%) had hyperfiltration (MDRD > 120 mL/min/1.73 m2), 2383 (54.2%) had chronic kidney disease (CKD) grade 2 (MDRD 60–90 mL/min/1.73 m2), and 221 (5.0%) had CKD grade 3 (MDRD 30–60 mL/min/1.73 m2). Multivariable analyses showed no eGFR change for patients in initial CKD grade 2, normal eGFR and hyperfiltration, and a significant increase in CKD grade 3. The RNPC© program avoids renal function impairment during the two first phases, regardless of the initial eGFR.

show abstract

Metabolic improvements during weight loss: The RNPC® cohort

et al. 2019

View full text Add to dashboard Cite

Weight loss and weight loss maintenance efficacy of a novel weight loss program: The retrospective RNPC® cohort

Cited by 10 publications

References 31 publications

The Impact of the COVID-19 Lockdown on Weight Loss and Body Composition in Subjects with Overweight and Obesity Participating in a Nationwide Weight-Loss Program: Impact of a Remote Consultation Follow-Up—The CO-RNPC Study

The Impact of the COVID-19 Lockdown on Weight Loss and Body Composition in Subjects with Overweight and Obesity Participating in a Nationwide Weight-Loss Program: Impact of a Remote Consultation Follow-Up—The CO-RNPC Study

A Specific High-Protein Weight Loss Program Does Not Impair Renal Function in Patients Who Are Overweight/Obese

Metabolic improvements during weight loss: The RNPC® cohort

Contact Info

Product

Resources

About