What have we learned from network meta-analyses applied to critical care?

Baez-Pravia, Orville; Montes-Andujar, Lara; Menéndez, Justo; Cardinal-Fernández, Pablo

doi:10.23736/s0375-9393.19.13267-1

Cited by 9 publications

(2 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The smoking cessation effect of different interventions was estimated based on the surface under the cumulative ranking curve (SUCRA). The SUCRA value ranges from 0 to 100%, where a SUCRA value of 100% indicates that the treatment was the most effective, and the smaller the value, the poorer the treatment effect [24][25][26].…”

Section: Discussionmentioning

confidence: 99%

Interventions to prevent pregnancy-induced hypertension: a systematic review and network meta-analysis

Guo

et al. 2023

Preprint

View full text Add to dashboard Cite

Objective A network meta-analysis based on randomized controlled trials was conducted to investigate the effects of different interventions in preventing pregnancy-induced hypertension. Methods English databases were searched for randomized controlled trials reporting different interventions in preventing pregnancy-induced hypertension. The risk of bias for the included trials was assessed using the Cochrane Handbook tool. Stata 15.1 software was used to perform network meta-analysis. Results A total of 47 studies involving 57,836 pregnant women were included in the network meta-analysis. For all included trials, 14 interventions were reported, which yielded 91 pairs of comparisons. The network meta-analysis showed that compared with Usual-care, interventions could significantly lower the incidence of hypertensive disorders of pregnancy, including yoga (odds ratio (OR) = 0.10, 95% confidence interval (CI) [0.02, 0.52]) and walking (OR = 0.51, 95% CI [0.27, 0.95]). Moreover, Yoga (OR = 0.11, 95% CI [0.02, 0.95]) and calcium supplementation (OR = 0.71, 95% CI [0.53, 0.94]) were superior to placebo in the prevention of pregnancy-induced hypertension. Finally, the surface under the cumulative ranking curve revealed that yoga had the highest probability of becoming the best intervention. Conclusions Maternal exercise (yoga and walking) or calcium supplementation might be the preventative tools for pregnancy-induced hypertension. However, given the limited number of trials and potential heterogeneity, more high-quality trials are needed to confirm the current findings.

show abstract

Section: Discussionmentioning

confidence: 99%

Interventions to prevent pregnancy-induced hypertension: a systematic review and network meta-analysis

Guo

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…Network meta-analysis (NMA) is a statistical tool that allows the analysis of the simultaneous comparison between interventions from different studies. In addition, it enables sorting all interventions according to their probability of being the best, even when they have never been compared in a face to face study [ 15 ]. Recently, NMAs have been applied to several diseases and their conclusions have been considered in recognized CPGs to increase the level of recommendations.…”

Section: Introductionmentioning

confidence: 99%

Safety and Efficacy of Devices Delivering Inhaled Antibiotics among Adults with Non-Cystic Fibrosis Bronchiectasis: A Systematic Review and a Network Meta-Analysis

Ramirez-Estrada¹,

Forero

Gallego

et al. 2022

Antibiotics

Self Cite

View full text Add to dashboard Cite

It remains unknown whether the type of aerosol generating device is affecting efficacy and safety among non-cystic fibrosis bronchiectasis (NCFB) adults. The proposal of this network meta-analysis (NMA) is to evaluate effectiveness and safety of inhaled antibiotics administered via dry powder inhaler (DPI) and via nebulizers (SVN) among adult patients with NCFB. Inclusion criteria were randomized-controlled trials, adults (≥18 years) with NCFB, and inhaled antibiotics administered via DPI as intervention. Search strategy was performed in PubMed, Web of Science, and Cochrane Library from 2000 to 2019. Sixteen trials (2870 patients) were included. Three trials (all ciprofloxacin) used DPIs and thirteen used SVN (three ciprofloxacin). Both DPI and SVN devices achieved similar safety outcomes (adverse events, antibiotic discontinuation, severe adverse events, and bronchospasm). Administration of ciprofloxacin via DPI significantly improved time to first exacerbation (87 days, 95%CI 34.3–139.7) and quality of life (MD -7.52; 95%CI -13.06 to -1.98) when compared with via SVN. No other significant differences were documented in clinical efficacy (at least one exacerbation, FEV1% predicted) and microbiologic response (bacterial eradication, emergence of new potential pathogens, and emergence of antimicrobial resistance) when comparing devices. Our NMA documented that time to first exacerbation and quality of life, were more favorable for DPIs. Decisions on the choice of devices should incorporate these findings plus other criteria, such as simplicity, costs or maintenance requirements.

show abstract

Association Between Spontaneous Breathing Trial Methods and Reintubation in Adult Critically Ill Patients

Ippolito,

Sardo,

Tripodi

et al. 2024

CHEST

View full text Add to dashboard Cite

What have we learned from network meta-analyses applied to critical care?

Cited by 9 publications

References 34 publications

Interventions to prevent pregnancy-induced hypertension: a systematic review and network meta-analysis

Interventions to prevent pregnancy-induced hypertension: a systematic review and network meta-analysis

Safety and Efficacy of Devices Delivering Inhaled Antibiotics among Adults with Non-Cystic Fibrosis Bronchiectasis: A Systematic Review and a Network Meta-Analysis

Association Between Spontaneous Breathing Trial Methods and Reintubation in Adult Critically Ill Patients

Contact Info

Product

Resources

About