Design has evolved from a craft into an academic discipline, but it still falls short on defining its own science. I review previous approaches to Design Science and conclude that the subjectobject dualism is the one of the main obstacles. I then apply the Metaphysics of Quality to overcome the dualism and propose Quality as the phenomenon of Design Science. Next, I propose to utilize the analysis of interaction effects as a mean to investigate Quality. Last, I recommend steps we can take to mature this new Design Science and strategies how we can gain the acknowledgement of the other sciences.