What is new in Brugada syndrome?

Bolek, Ondřej; Marek, Dan; Táborský, Miloš

doi:10.1016/j.crvasa.2013.09.003

Cited by 1 publication

(1 citation statement)

References 33 publications

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“…2 It is a genetic disorder with alterations in the SCN5A gene (10-30% cases) and 300 mutations have been described. 3,4 There could be other genes affected, which can cause a variant of Brugada syndrome, including the genes coding for alpha1-and beta2b-subunits of the L-type calcium channel (CACNA1C and CACNB2), which are thought to cause a syndrome of precordial ST elevation, sudden death, and short QT interval. 5,6 The most common manifestations is syncope or cardiac arrest, which occur during sleep, but many patients remain asymptomatic.…”

Section: Introductionmentioning

confidence: 99%

Brugada syndrome diagnosed after ventricular fibrillation with anamnesis of fever

Nehaj¹,

Mokáň²,

Sokol³

et al. 2019

Cor Vasa

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SÚHRNSyndróm Brugadových je genetická porucha charakterizovaná komorovými tachyarytmiami, ktoré môžu viesť k zástave srdca, synkope alebo náhlej srdcovej smrti. Tento syndróm je asociovaný s niekoľkými elektrokardiografi ckými obrazcami, ako sú napríklad elevácie ST v predných prekordiálnych zvodoch a nekompletná blokáda pravého Tawarovho ramienka. Mnoho ľudí so syndrómom Brugadových nemá žiadne príznaky, ak áno, môžu sa vyskytnúť kedykoľvek a niekedy môžu byť vyvolané horúčkou, alkoholom alebo dehydratáciou. Implantácia implantovateľného srdcového defi brilátora je jediná liečba, ktorá sa osvedčila ako účinná pri liečbe a prevencii náhlej srdcovej smrti u pacientov so syndrómom Brugadových. Uvádzame zriedkavú kazuistiku syndrómu Brugadových, ktorý sa manifestoval komorovou fi briláciou vyvolanou horúčkou. ABSTRACTBrugada syndrome is a genetic disorder characterized by ventricular tachyarrhythmias that may lead to cardiac arrest, syncope or sudden cardiac death. This syndrome is associated with several electrocardiographic patterns such as ST elevations in the anterior precordial leads and incomplete right bundle branch block. Many people with Brugada syndrome do not have any symptoms if yes, they can occur at any time and are sometimes triggered by high temperature, alcohol or dehydration. The implantation of an automatic implantable cardiac defi brillator is the only treatment proven effective in treating and preventing sudden cardiac death in patients with Brugada syndrome. We present a rare case report of Brugada syndrome induced by fever which was manifested with ventricular fi brillation.

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