What is your diagnosis? Fine‐needle aspirate of ulcerative skin lesions in a dog

Gupta, Anuj; Stroup, Shannon; Dedeaux, Andrea; Bauer, Rudy W.; Gaunt, Stephen D.

doi:10.1111/j.1939-165x.2011.00340.x

Cited by 6 publications

(4 citation statements)

References 4 publications

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“…There are limited reports in the literature regarding adverse effects; however, anecdotally, there would appear to be very few adverse events when using CA. Potential adverse reactions reported in association with CA use include dermatological disease following subcutaneous injections in dogs treated for NIME17 18 and infiltrative lung disease 19. The incidence of myelosuppression following CA administration for the treatment of canine lymphoma (600 mg/m 2 intravenously over 48 hours) has been assessed in a previous publication, and their results showed that 10 of 14 patients developed at least one cytopenia 20.…”

Section: Introductionmentioning

confidence: 99%

Low frequency of pre‐treatment and post‐treatment haematological abnormalities in dogs with non‐infectious meningoencephalitis treated with cytosine arabinoside and prednisolone

Keegan¹,

Rose²,

Khan

et al. 2019

Veterinary Record Open

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BackgroundCytosine arabinoside (CA) and prednisolone are drugs commonly used together in the management of canine non-infectious meningoencephalitis (NIME). The aim of this study was to report the haematological findings before and after CA and prednisolone treatment and identify any adverse haematological events in this clinical setting, following the veterinary cooperative oncology group established common terminology criteria for recording adverse events following administration of chemotherapy or biological antineoplastic therapy.ResultsWhile 48 patients with a presumptive diagnosis of NIME had pretreatment haematology results, only 12 patients met the inclusion criteria of also having post-treatment haematology results available for review after being treated with prednisolone and CA at a standard dose (200 mg/m2) in a single referral hospital in the UK. Forty-nine post-treatment haematology results were available for these 12 patients.ConclusionsFour adverse haematological events were identified in four patients. None of these events were convincingly attributable to CA administration.

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Section: Introductionmentioning

confidence: 99%

Low frequency of pre‐treatment and post‐treatment haematological abnormalities in dogs with non‐infectious meningoencephalitis treated with cytosine arabinoside and prednisolone

Keegan¹,

Rose²,

Khan

et al. 2019

Veterinary Record Open

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“…Clindamycin is effective in suppressing the replication and dissemination of tachyzoites but does not appear to be effective against encysted bradyzoites (Dubey and Lappin, 2006). Eight of the eleven dogs previously reported with cutaneous neosporosis either died or were euthanized, but fi ve of the eleven dogs showed clinical improvement or had resolution of the cutaneous lesions with clindamycin therapy (Dubey et al, 1988;Dubey et al, 1995;Fritz et al, 1997;Perl et al, 1998;Poli et al, 1998;La Perle et al 2001;Tarantino et al, 2001;Ordeix et al, 2002;Boyd et al, 2005;Gupta et al, 2011). The dog of the present case was treated with clindamycin for six weeks, and recovered completely.…”

Section: Discussionmentioning

confidence: 67%

“…Infection of Neospora restricted to the skin is rare (Dubey et al, 1988;Dubey et al, 1995;Fritz et al, 1997;Perl et al, 1998;Poli et al, 1998;La Perle et al, 2001;Tarantino et al, 2001;Ordeix et al, 2002;Boyd et al, 2005;Gupta et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Cutane neosporose bij een volwassen hond in België

Schuyter¹,

Cock²,

Lemmens³

2013

Vlaams Diergeneeskundig Tijdschrift

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A twelve-year-old female spayed Greyhound was presented with ulcerative nodular lesions,generalized weakness and pain. At the time of presentation, the dog was receiving prednisolonefor a presumptive diagnosis of cervical discus hernia. Fine needle aspiration of the nodular lesionsdemonstrated protozoal tachyzoites. Immunohistochemistry confi rmed the diagnosis of Neosporacaninum infection. Clindamycin therapy, together with the withdrawal of immunosuppressivemedication, resulted in complete remission. This report documents the fi rst case of cutaneousneosporosis in Belgium.

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“…(2013) Maltese a 6 FS Cutaneous IHC and PCR on swabs of cutaneous lesions. IFAT titre: 1:1,600 Euthanised Gupta et al. (2011) Rottweiler a 2 F Neurological/myopathic + gastric nodulation IFAT titre: 1:400.…”

Section: Resultsmentioning

confidence: 99%

Seroprevalence of Neospora caninum in dogs from greater Sydney, Australia unchanged from 1997 to 2019 and worldwide review of adult-onset of canine neosporosis

Barker

Wigney²,

Child

et al. 2021

Current Research in Parasitology & Vector-Borne Diseases

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What is your diagnosis? Fine‐needle aspirate of ulcerative skin lesions in a dog

Cited by 6 publications

References 4 publications

Low frequency of pre‐treatment and post‐treatment haematological abnormalities in dogs with non‐infectious meningoencephalitis treated with cytosine arabinoside and prednisolone

Low frequency of pre‐treatment and post‐treatment haematological abnormalities in dogs with non‐infectious meningoencephalitis treated with cytosine arabinoside and prednisolone

Cutane neosporose bij een volwassen hond in België

Seroprevalence of Neospora caninum in dogs from greater Sydney, Australia unchanged from 1997 to 2019 and worldwide review of adult-onset of canine neosporosis

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