2012
DOI: 10.5639/gabij.2012.0102.016
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What lessons can be learned from the launch of generic clopidogrel?

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Cited by 32 publications
(38 citation statements)
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“…Responding to efforts by the originator company to retain sales, authorities adopted 'pragmatic approaches' to enhance generics prescribing, e.g. mandatory generics substitution, educational activities, see Table 2 [23,24]. Still, the differences in the reimbursed prices of generic clopidogrel versus the originator were high across Europe, especially briefl y after launch, but decreasing over time.…”
Section: Somementioning
confidence: 99%
“…Responding to efforts by the originator company to retain sales, authorities adopted 'pragmatic approaches' to enhance generics prescribing, e.g. mandatory generics substitution, educational activities, see Table 2 [23,24]. Still, the differences in the reimbursed prices of generic clopidogrel versus the originator were high across Europe, especially briefl y after launch, but decreasing over time.…”
Section: Somementioning
confidence: 99%
“…In addition, potentially liberating monies to fund new innovative drugs [6][7][8][9][10][11]40,71,72]. However, this philosophy has not always been followed by individual companies, some of whom try and manipulate the market to maintain sales of their originator products for as long as possible [6,52,54,74]. The World Health Organization (WHO) also endorses the use of generics when discussing the rational use of medicines as well as potential strategies to release resources to help maximise health gain with available budgets [17,40,63,70,75].…”
Section: Introductionmentioning
confidence: 99%
“…The various initiatives can be divided into supply-side reforms and demand-side reforms. Supply-side reforms include measures to lower the price of generics, accelerate their marketing authorisation, reference pricing for the molecule (Anatomical Therapeutic Classification -ATC -Level 5 [76]), the class (ATC Level 4) or the therapeutic area (ATC Level 3), as well as compulsory price cuts when target budgets are being exceeded [1][2][3][4][5][6][7][8]10,11,14,15,[31][32][33][34][35]37,38,[40][41][42]44,52,77,78]. Demand-side measures include those to enhance the prescribing, requesting and dispensing of generics versus originators, as well as enhance the prescribing of generics in a class or related class versus still patented products where all drugs in the class are seen as essentially similar for all or nearly all patients [1][2][3][4][5][6][7][8][9][10][11]15,[31][32][33][34][35]…”
Section: Introductionmentioning
confidence: 99%
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