Ever since those diseases that infectious agents cause (infectious diseases) were logically deduced to be transmissible, contagious diseases in the manner of the contagion theorists who formed a concept of such diseases even before such agents (pathogens) were discovered, the outcomes of the event in which the infectious disease is brought about have been seen as direct consequences of infection. And since the time of Mechnikov, immunity to such severe outcomes has been seen as a consequence of the prevention of the pathogen’s spread in healthy individuals by an “immune system” that is made up of cells and substances that destroy the pathogen. After all, Mechnikov had logically deduced that “every time the organism enjoys immunity, the infectious agent falls prey” to the constituents of such a system. Consequently, the severe outcomes of the event in which the infectious disease is brought about were logically deduced to appear every time the infectious agent does not fall prey to the immune system. And ultimately, this was logically deduced to be due to the weakening of this immune system by underlying conditions in unhealthy individuals. Therefore, as disabilities and deaths in monkeypox patients rise in the United States, such severe outcomes are being attributed to such underlying conditions which are expected to prevent the actual monkeypox virus from being cleared by weakening the immune system. And as treatments with an antiviral drug that slows down viral replication failed to bring about the disappearance of such severe outcomes, it appears that disabilities and deaths cannot be prevented whenever severe outcomes appear in infected individuals with such pre-existing conditions. But we realize that such logically deduced hopelessness has no place in reality upon considering the fact that some monkeypox patients who were killed by such severe outcomes, such as the two individuals in the experiences reported by Spain’s Health Ministry, were healthy at the time of infection. And we see the path to the solution of the problem when we realize, upon visualizing the reality in which biological phenomena occur with the Einsteinian method which does not make logical deductions from experience in order to account for data and their mutual relations, that the event in which the infectious disease is brought about by the pathogen is one in which different diseases in the immunological spectrum of the infectious disease co-manifest to bring about outcomes of different kinds in different individuals as a result of the absence of conditions that prevent pathological mechanisms from responding to their different causes. And such immunological conditions that permit all the causes of the diseases in this spectrum to be harbored uneventfully (asymptomatically) may be absent not only in the unhealthy but even in healthy individuals either as a result of their failure to appear when necessitated by infection or vaccination or because of their disappearance. More people are infected with the pathogen than can be detected on the basis of the appearance of such expected outcomes as those in monkeypox patients with skin conditions because only a subset of the infected are exposed to the causes of diseases that co-manifest to bring about such outcomes and immunological conditions are still present even in some members of that subset. The reduction in the number of cases in which such expected outcomes are observed therefore does not imply a reduction in the number of cases. And if the absence of immunological conditions as well as the presence of the causes of such spectral diseases that co-manifest to bring about severe outcomes in the infected should become sufficiently widespread before we understand them enough to become able to bring about such protective conditions with precision wherever they are absent, our populations will be decimated by such severe outcomes even if their members were as healthy as the Athenians of Pericles’s day were just before such severe outcomes disabled and killed them. “It was generally agreed that in respect of other ailments no season had ever been so healthy,” wrote the great medical historian, Thucydides. The elucidation of such immunological conditions therefore ought to be the topmost priority in public health now.