What's in wine? A clinician's perspective,

Haseeb, Sohaib; Alexander, Bryce; Santi, Ricardo López; Liprandi, Álvaro Sosa; Baranchuk, Adrián

doi:10.1016/j.tcm.2018.06.010

Cited by 45 publications

(25 citation statements)

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“…Questions were not forced and respondents were permitted to select multiple response choices depending on the question content. The survey was developed using topics and themes identified in updated literature reviews [ 1 , 2 , 3 , 5 , 6 , 7 ] and with input from the study investigators.…”

Section: Methodsmentioning

confidence: 99%

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Attitudes and Recommendations of Physicians towards Alcohol Consumption and Cardiovascular Health: A Perspective from Argentina

et al. 2018

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Despite epidemiological findings of improvements in cardiovascular risk factors with a light-to-moderate intake of alcohol, many misconceptions remain regarding alcohol intake and the risks and benefits of consumption. We sought to examine physician attitudes and recommendations regarding alcohol intake in a cohort of Argentine physicians and to establish their sources of knowledge. An online national survey was distributed through the Argentine Federation of Cardiology (FAC) to cardiologists, internal medicine specialists, general and other subspecialty physicians in Argentina. The survey was completed by 745 physicians, of whom 671 (90%) were cardiologists. In total, 35% of physicians viewed moderate alcohol intake to be beneficial for cardiovascular health, 36% believed only wine offered such benefits, 24% viewed any intake to be harmful, and 5% had other opinions. More than half (57%) self-reported their knowledge came from academic sources. Regarding knowledge of drinking guidelines, only 41% of physicians were aware of the concept of “standard drink”. Physicians were generally not comfortable converting standard drinks into other metric units, however men tended to be more comfortable than women (p = 0.052). Physicians were not satisfied with their knowledge of drinking guidelines (3.01 ± 2.73, on a 0–10 scale). Physicians were generally comfortable in counselling patients regarding safe limits of consumption (6.22 ± 3.20, on a 0–10 scale). Argentine physicians were not satisfied with their knowledge of alcohol consumption guidelines or their understanding of the reported metrics. Only one-third of study participants viewed moderate alcohol intake as beneficial for cardiovascular health. This study shows the necessity to optimize the sources of knowledge.

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Section: Methodsmentioning

confidence: 99%

“…Alcoholic beverages have been consumed for thousands of years [ 1 , 2 , 3 ]. In 2017, global wine consumption was 243 million hectoliters (mhl), with Argentina being the eighth largest global consumer of wine (8.9 mhl) [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Attitudes and Recommendations of Physicians towards Alcohol Consumption and Cardiovascular Health: A Perspective from Argentina

et al. 2018

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“…Its higher polyphenol content favourably modifies oxidation and inflammation parameters related to arteriosclerosis by different pathways: higher NO availability (improving endothelial function), increases in HDL cholesterol levels and anti-aggregation/profibrinolytic/anti-inflammation properties ( Table 2). [75][76][77][78][79] Beer is another type of fermented beverage with moderate polyphenol content that has cardioprotective effects comparable to wine. 80,81 Both alcoholic and non-alcoholic beer improve inflammatory biomarkers profile, homocysteine and folic acid levels ( Table 2).…”

Section: Fish and Seafoodmentioning

confidence: 99%

Deciphering the Riddles in Nutrition and Cardiovascular Disease

Carro¹,

Panisello²

2019

Eur Cardiol

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Cardiovascular disease is the leading global cause of death in Western countries, and its development is largely associated with unhealthy dietary patterns. A large body of scientific evidence has reported that nutrition might be the most preventive factor of cardiovascular disease death and could even reverse heart disease. Processes of chronic inflammation and oxidative distress share triggers that are modifiable by nutrition. This review aimed to identify potential targets (food patterns, single foods or individual nutrients) for cardiovascular disease prevention, and analyse the mechanisms implicated in their cardioprotective effects.

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“…Here, emphasis will be placed on red grape polyphenols. For instance, wine polyphenols represent an important dietary source with flavonoids accounting for >85%, ≥1 g/L of total phenolics [22]. A minor component is represented by derivatives of carboxylic acids, hydroxycinnamate, tannins, and RES [23].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances on the Anti-Inflammatory and Antioxidant Properties of Red Grape Polyphenols: In Vitro and In Vivo Studies

Magrone

Russo

et al. 2019

Antioxidants

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In this review, special emphasis will be placed on red grape polyphenols for their antioxidant and anti-inflammatory activities. Therefore, their capacity to inhibit major pathways responsible for activation of oxidative systems and expression and release of proinflammatory cytokines and chemokines will be discussed. Furthermore, regulation of immune cells by polyphenols will be illustrated with special reference to the activation of T regulatory cells which support a tolerogenic pathway at intestinal level. Additionally, the effects of red grape polyphenols will be analyzed in obesity, as a low-grade systemic inflammation. Also, possible modifications of inflammatory bowel disease biomarkers and clinical course have been studied upon polyphenol administration, either in animal models or in clinical trials. Moreover, the ability of polyphenols to cross the blood–brain barrier has been exploited to investigate their neuroprotective properties. In cancer, polyphenols seem to exert several beneficial effects, even if conflicting data are reported about their influence on T regulatory cells. Finally, the effects of polyphenols have been evaluated in experimental models of allergy and autoimmune diseases. Conclusively, red grape polyphenols are endowed with a great antioxidant and anti-inflammatory potential but some issues, such as polyphenol bioavailability, activity of metabolites, and interaction with microbiota, deserve deeper studies.

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What's in wine? A clinician's perspective,

Cited by 45 publications

References 100 publications

Attitudes and Recommendations of Physicians towards Alcohol Consumption and Cardiovascular Health: A Perspective from Argentina

Attitudes and Recommendations of Physicians towards Alcohol Consumption and Cardiovascular Health: A Perspective from Argentina

Deciphering the Riddles in Nutrition and Cardiovascular Disease

Recent Advances on the Anti-Inflammatory and Antioxidant Properties of Red Grape Polyphenols: In Vitro and In Vivo Studies

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